Gene detail

B2C23_RS07565

Histidine kinase, Hybrid

Clostridioides difficile · GCF_900164445

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164445#B2C23_RS07565Stable P2CS identifier used across views.
GenomeGCF_900164445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484794Run 6 · 30 sequences · id 100% · cov 80%
External referencesWP_021371824.1 · MIST4 B2C23_RS07565RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa852 aa
HisKA: 344-410 aa (67 aa)1HATPase_c: 458-576 aa (119 aa)2Response_reg: 592-696 aa (105 aa)3Response_reg: 731-848 aa (118 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:4.57e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.43e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:8.03e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:5.94e-27:848:118:111
  • Raw architecture: HisKA:344:4.57e-18:410:67:64#HATPase_c:458:5.43e-25:576:120:109#Response_reg:592:8.03e-22:696:105:111#Response_reg:731:5.94e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164445::NZ_FUMO01000003.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span506627-511195Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375124_01503RefSeq proteinWP_021371824.1
Context group IDGCF_900164445::NZ_FUMO01000003.1::G00045
Context members
B2C23_RS07555B2C23_RS07565
Partner locus tags
B2C23_RS07555B2C23_RS07565
Partner old locus tags
SAMEA3375124_01501SAMEA3375124_01503
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021371824.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C23_RS07565Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375124_01503Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUMO01000003.1Sequence record reported by the local genomic context database.
Genomic interval508 637-511 195 nt2 559 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span506 627-511 195 ntGCF_900164445::NZ_FUMO01000003.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164445::NZ_FUMO01000003.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUMO01000003.1All displayed genes belong to this local TCS context.
Neighborhood span506 627-511 195 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
506 627 nt511 195 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C23_RS07555GCF_900164445#B2C23_RS07555
RRRpfG

506 627-508 267 nt · Forward (+)

Old locus SAMEA3375124_01501RefSeq WP_009901919.1
B2C23_RS07565GCF_900164445#B2C23_RS07565
HKHybridCurrent focus

508 637-511 195 nt · Forward (+)

Old locus SAMEA3375124_01503RefSeq WP_021371824.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484794Run 6 · HK · 30 sequences
Representative sequenceGCF_000449065#QCK_RS03940Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484794

Simplified PFAM architecture for HKOC_0484794

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484794
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449065#QCK_RS03940

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164445
Assembly16780_8#58 · Scaffoldhaploid
Genome composition4 222 769 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key