1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw token
HAMP:94:0.00000000532:171:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
B2C23_RS07445
Histidine kinase, Classic
Clostridioides difficile · GCF_900164445
ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164445#B2C23_RS07445Stable P2CS identifier used across views.
GenomeGCF_900164445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa407 aa
Domain-by-domain annotation3 items
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw token
HisKA:183:0.00000000333:248:66:643 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw token
HATPase_c:298:4.46e-26:404:107:109- Raw architecture: HAMP:94:0.00000000532:171:78:69#HisKA:183:0.00000000333:248:66:64#HATPase_c:298:4.46e-26:404:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900164445::NZ_FUMO01000003.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span482406-484541Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375124_01478RefSeq proteinWP_330363505.1
Context group ID
GCF_900164445::NZ_FUMO01000003.1::G00043Context members
B2C23_RS07445B2C23_RS07450
Partner locus tags
B2C23_RS07445B2C23_RS07450
Partner old locus tags
SAMEA3375124_01478SAMEA3375124_01479
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330363505.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagB2C23_RS07445Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375124_01478Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUMO01000003.1Sequence record reported by the local genomic context database.
Genomic interval482 406-483 629 nt1 224 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span482 406-484 541 ntGCF_900164445::NZ_FUMO01000003.1::G00043
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900164445::NZ_FUMO01000003.1::G00043Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUMO01000003.1All displayed genes belong to this local TCS context.
Neighborhood span482 406-484 541 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
482 406 nt484 541 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
B2C23_RS07445GCF_900164445#B2C23_RS07445
HKClassicCurrent focus
482 406-483 629 nt · Reverse (-)
B2C23_RS07450GCF_900164445#B2C23_RS07450
RROmpR
483 849-484 541 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0203575Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2380014
Simplified PFAM architecture for HKOC_2380014
PFAM domain coverage: 223 / 407 aa (54.8%)
1 aa407 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[121-171] | HisKA[184-248] | HATPase_c[298-404]
- Domain count: 3
- Matched identifier: HKOC_2380014
- Positioned domains: HAMP 121-171 ; HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0203575
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164445
Assembly16780_8#58 · Scaffoldhaploid
Genome composition4 222 769 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key