Gene detail

B2C23_RS04000

Histidine kinase, Classic

Clostridioides difficile · GCF_900164445

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900164445#B2C23_RS04000Stable P2CS identifier used across views.
GenomeGCF_900164445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1748402Run 6 · 69 sequences · id 100% · cov 80%
External referencesWP_021421585.1 · MIST4 B2C23_RS04000RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 450 aa (39.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
HisKA: 228-296 aa (69 aa)1HATPase_c: 343-449 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
228-296 aa · 69 aa · 15.3% of protein
Raw tokenHisKA:228:0.000000000000217:296:69:64
2 HATPase_c#2
343-449 aa · 107 aa · 23.8% of protein
Raw tokenHATPase_c:343:1.26e-27:449:108:109
  • Raw architecture: HisKA:228:0.000000000000217:296:69:64#HATPase_c:343:1.26e-27:449:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900164445::NZ_FUMO01000002.1::G00025
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span228108-229460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375124_00793RefSeq proteinWP_021421585.1
Context group IDGCF_900164445::NZ_FUMO01000002.1::G00025
Context members
B2C23_RS04000
Partner locus tags
B2C23_RS04000
Partner old locus tags
SAMEA3375124_00793
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021421585.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C23_RS04000Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375124_00793Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUMO01000002.1Sequence record reported by the local genomic context database.
Genomic interval228 108-229 460 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span228 108-229 460 ntGCF_900164445::NZ_FUMO01000002.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164445::NZ_FUMO01000002.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUMO01000002.1All displayed genes belong to this local TCS context.
Neighborhood span228 108-229 460 nt1 353 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
228 108 nt229 460 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

B2C23_RS04000GCF_900164445#B2C23_RS04000
HKClassicCurrent focus

228 108-229 460 nt · Reverse (-)

Old locus SAMEA3375124_00793RefSeq WP_021421585.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748402Run 6 · HK · 69 sequences
Representative sequenceGCF_000451745#QSK_RS09750Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748402

Simplified PFAM architecture for HKOC_1748402

PFAM domain coverage: 167 / 467 aa (35.8%)

1 aa467 aa
HisKA: 245-306 aaHisKAHATPase_c: 362-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-306] | HATPase_c[362-466]
  • Domain count: 2
  • Matched identifier: HKOC_1748402
  • Positioned domains: HisKA 245-306 ; HATPase_c 362-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS09750

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164445
Assembly16780_8#58 · Scaffoldhaploid
Genome composition4 222 769 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key