Gene detail

B2C87_RS14685

Histidine kinase, Classic

Clostridioides difficile · GCF_900164305

ClassHKTypeClassicLength618 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900164305#B2C87_RS14685Stable P2CS identifier used across views.
GenomeGCF_900164305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0977608Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_009902631.1 · A0AB74QCZ3 · MIST4 B2C87_RS14685RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length618 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 618 aa (46.9%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa618 aa
PAS_4: 246-354 aa (109 aa)1HisKA: 363-432 aa (70 aa)2HATPase_c: 479-589 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_4#1
246-354 aa · 109 aa · 17.6% of protein
Raw tokenPAS_4:246:0.000000000199:354:115:110
2 HisKA#2
363-432 aa · 70 aa · 11.3% of protein
Raw tokenHisKA:363:0.0000000000000908:432:70:64
3 HATPase_c#3
479-589 aa · 111 aa · 18.0% of protein
Raw tokenHATPase_c:479:8.57e-28:589:111:109
  • Raw architecture: PAS_4:246:0.000000000199:354:115:110#HisKA:363:0.0000000000000908:432:70:64#HATPase_c:479:8.57e-28:589:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900164305::NZ_FUMS01000006.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span26445-28301Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375072_02941RefSeq proteinWP_009902631.1
Context group IDGCF_900164305::NZ_FUMS01000006.1::G00002
Context members
B2C87_RS14685
Partner locus tags
B2C87_RS14685
Partner old locus tags
SAMEA3375072_02941
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009902631.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QCZ3Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QCZ3_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C87_RS14685Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375072_02941Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUMS01000006.1Sequence record reported by the local genomic context database.
Genomic interval26 445-28 301 nt1 857 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span26 445-28 301 ntGCF_900164305::NZ_FUMS01000006.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164305::NZ_FUMS01000006.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUMS01000006.1All displayed genes belong to this local TCS context.
Neighborhood span26 445-28 301 nt1 857 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 445 nt28 301 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

B2C87_RS14685GCF_900164305#B2C87_RS14685
HKClassicCurrent focus

26 445-28 301 nt · Forward (+)

Old locus SAMEA3375072_02941RefSeq WP_009902631.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0977608Run 6 · HK · 10 sequences
Representative sequenceGCF_000155025#UAB_RS0209065Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0977608

Simplified PFAM architecture for HKOC_0977608

PFAM domain coverage: 290 / 618 aa (46.9%)

1 aa618 aa
PAS_4: 246-354 aaPAS_4HisKA: 363-432 aaHisKAHATPase_c: 479-589 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[246-354] | HisKA[363-432] | HATPase_c[479-589]
  • Domain count: 3
  • Matched identifier: HKOC_0977608
  • Positioned domains: PAS_4 246-354 ; HisKA 363-432 ; HATPase_c 479-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0209065

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164305
Assembly16780_8#6 · Scaffoldhaploid
Genome composition4 326 883 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key