Gene detail

B2B14_RS01330

Histidine kinase, Classic

Clostridioides difficile · GCF_900164295

ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164295#B2B14_RS01330Stable P2CS identifier used across views.
GenomeGCF_900164295Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2354501Run 6 · 27 sequences · id 100% · cov 80%
External referencesWP_021371204.1 · MIST4 B2B14_RS01330RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
HisKA: 185-250 aa (66 aa)1HATPase_c: 296-408 aa (113 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw tokenHisKA:185:0.000000000174:250:66:64
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw tokenHATPase_c:296:2.75e-24:408:113:109
  • Raw architecture: HisKA:185:0.000000000174:250:66:64#HATPase_c:296:2.75e-24:408:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164295::NZ_FULK01000001.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span275857-277750Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375089_00274RefSeq proteinWP_021371204.1
Context group IDGCF_900164295::NZ_FULK01000001.1::G00044
Context members
B2B14_RS01325B2B14_RS01330
Partner locus tags
B2B14_RS01325B2B14_RS01330
Partner old locus tags
SAMEA3375089_00273SAMEA3375089_00274
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021371204.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B14_RS01330Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375089_00274Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FULK01000001.1Sequence record reported by the local genomic context database.
Genomic interval276 518-277 750 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span275 857-277 750 ntGCF_900164295::NZ_FULK01000001.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164295::NZ_FULK01000001.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FULK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span275 857-277 750 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
275 857 nt277 750 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B14_RS01325GCF_900164295#B2B14_RS01325
RROmpR

275 857-276 528 nt · Forward (+)

Old locus SAMEA3375089_00273RefSeq WP_004454472.1
B2B14_RS01330GCF_900164295#B2B14_RS01330
HKClassicCurrent focus

276 518-277 750 nt · Forward (+)

Old locus SAMEA3375089_00274RefSeq WP_021371204.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2354501Run 6 · HK · 27 sequences
Representative sequenceGCF_000449045#QCI_RS08545Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2354501

Simplified PFAM architecture for HKOC_2354501

PFAM domain coverage: 178 / 410 aa (43.4%)

1 aa410 aa
HisKA: 185-250 aaHisKAHATPase_c: 297-408 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[185-250] | HATPase_c[297-408]
  • Domain count: 2
  • Matched identifier: HKOC_2354501
  • Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449045#QCI_RS08545

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164295
Assembly16780_8#23 · Scaffoldhaploid
Genome composition4 125 064 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 52 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key