Gene detail

B2C73_RS15085

Histidine kinase, Classic

Clostridioides difficile · GCF_900164115

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_900164115#B2C73_RS15085Stable P2CS identifier used across views.
GenomeGCF_900164115Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676374Run 6 · 66 sequences · id 100% · cov 80%
External referencesWP_021397421.1 · MIST4 B2C73_RS15085RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.0000000000000742:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:3.91e-25:368:110:109
  • Raw architecture: HisKA:148:0.0000000000000742:211:64:64#HATPase_c:260:3.91e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_900164115::NZ_FUME01000005.1::G00030
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span160401-166125Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375098_03001RefSeq proteinWP_021397421.1
Context group IDGCF_900164115::NZ_FUME01000005.1::G00030
Context members
B2C73_RS15085B2C73_RS15090B2C73_RS15095B2C73_RS15100B2C73_RS15105
Partner locus tags
B2C73_RS15085B2C73_RS15090B2C73_RS15095B2C73_RS15100B2C73_RS15105
Partner old locus tags
SAMEA3375098_03001SAMEA3375098_03002SAMEA3375098_03003SAMEA3375098_03004SAMEA3375098_03005

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021397421.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C73_RS15085Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375098_03001Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUME01000005.1Sequence record reported by the local genomic context database.
Genomic interval160 401-161 516 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span160 401-166 125 ntGCF_900164115::NZ_FUME01000005.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164115::NZ_FUME01000005.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUME01000005.1All displayed genes belong to this local TCS context.
Neighborhood span160 401-166 125 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
160 401 nt166 125 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

B2C73_RS15085GCF_900164115#B2C73_RS15085
HKClassicCurrent focus

160 401-161 516 nt · Reverse (-)

Old locus SAMEA3375098_03001RefSeq WP_021397421.1
B2C73_RS15090GCF_900164115#B2C73_RS15090
RROmpR

161 552-162 250 nt · Reverse (-)

Old locus SAMEA3375098_03002RefSeq WP_021422705.1
B2C73_RS15095GCF_900164115#B2C73_RS15095
RROmpR

162 631-163 311 nt · Reverse (-)

Old locus SAMEA3375098_03003RefSeq WP_003432361.1
B2C73_RS15100GCF_900164115#B2C73_RS15100
HKClassic

163 361-165 376 nt · Reverse (-)

Old locus SAMEA3375098_03004RefSeq WP_021422693.1
B2C73_RS15105GCF_900164115#B2C73_RS15105
RROmpR

165 448-166 125 nt · Reverse (-)

Old locus SAMEA3375098_03005RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676374Run 6 · HK · 66 sequences
Representative sequenceGCF_000450145#QK3_RS16740Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676374

Simplified PFAM architecture for HKOC_2676374

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676374
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS16740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164115
Assembly16780_8#32 · Contighaploid
Genome composition4 282 662 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 112 · HK 55 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key