Gene detail

B2C73_RS08245

Histidine kinase, Classic

Clostridioides difficile · GCF_900164115

ClassHKTypeClassicLength272 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900164115#B2C73_RS08245Stable P2CS identifier used across views.
GenomeGCF_900164115Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2892347Run 6 · 27 sequences · id 100% · cov 80%
External referencesWP_226811947.1 · MIST4 B2C73_RS08245RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length272 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage144 / 272 aa (52.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa272 aa
HisKA: 65-122 aa (58 aa)1HATPase_c: 172-257 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
65-122 aa · 58 aa · 21.3% of protein
Raw tokenHisKA:65:0.00000000244:122:58:64
2 HATPase_c#2
172-257 aa · 86 aa · 31.6% of protein
Raw tokenHATPase_c:172:0.00000000000000195:257:91:109
  • Raw architecture: HisKA:65:0.00000000244:122:58:64#HATPase_c:172:0.00000000000000195:257:91:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900164115::NZ_FUME01000002.1::G00022
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span375657-376475Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375098_01662RefSeq proteinWP_226811947.1
Context group IDGCF_900164115::NZ_FUME01000002.1::G00022
Context members
B2C73_RS08245
Partner locus tags
B2C73_RS08245
Partner old locus tags
SAMEA3375098_01662
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_226811947.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C73_RS08245Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375098_01662Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUME01000002.1Sequence record reported by the local genomic context database.
Genomic interval375 657-376 475 nt819 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span375 657-376 475 ntGCF_900164115::NZ_FUME01000002.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164115::NZ_FUME01000002.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUME01000002.1All displayed genes belong to this local TCS context.
Neighborhood span375 657-376 475 nt819 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
375 657 nt376 475 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

B2C73_RS08245GCF_900164115#B2C73_RS08245
HKClassicCurrent focus

375 657-376 475 nt · Forward (+)

Old locus SAMEA3375098_01662RefSeq WP_226811947.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2892347Run 6 · HK · 27 sequences
Representative sequenceGCF_004314545#E0O41_RS01100Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2892347

Simplified PFAM architecture for HKOC_2892347

PFAM domain coverage: 145 / 295 aa (49.2%)

1 aa295 aa
HisKA: 86-145 aaHisKAHATPase_c: 195-279 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[86-145] | HATPase_c[195-279]
  • Domain count: 2
  • Matched identifier: HKOC_2892347
  • Positioned domains: HisKA 86-145 ; HATPase_c 195-279
Cluster members and taxonomy
Visualization

Representative gene: GCF_004314545#E0O41_RS01100

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164115
Assembly16780_8#32 · Contighaploid
Genome composition4 282 662 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 112 · HK 55 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key