Gene detail

DK474_RS02655

Histidine kinase, Classic

Clostridioides difficile · GCF_900096205

ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096205#DK474_RS02655Stable P2CS identifier used across views.
GenomeGCF_900096205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359833Run 6 · 9 sequences · id 100% · cov 80%
External referencesWP_042743945.1 · MIST4 DK474_RS02655RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 529 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa529 aa
HisKA: 308-374 aa (67 aa)1HATPase_c: 427-512 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
308-374 aa · 67 aa · 12.7% of protein
Raw tokenHisKA:308:0.0000000000000154:374:67:64
2 HATPase_c#2
427-512 aa · 86 aa · 16.3% of protein
Raw tokenHATPase_c:427:0.000000046:512:90:109
  • Raw architecture: HisKA:308:0.0000000000000154:374:67:64#HATPase_c:427:0.000000046:512:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096205::NZ_FMKX01000001.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span582682-584956Genomic interval covered by the local TCS group.
Context group IDGCF_900096205::NZ_FMKX01000001.1::G00033
Context members
DK474_RS02655DK474_RS02660
Partner locus tags
DK474_RS02655DK474_RS02660
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_042743945.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK474_RS02655Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMKX01000001.1Sequence record reported by the local genomic context database.
Genomic interval582 682-584 271 nt1 590 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span582 682-584 956 ntGCF_900096205::NZ_FMKX01000001.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096205::NZ_FMKX01000001.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMKX01000001.1All displayed genes belong to this local TCS context.
Neighborhood span582 682-584 956 nt2 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
582 682 nt584 956 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK474_RS02660GCF_900096205#DK474_RS02660
RROmpR

584 240-584 956 nt · Reverse (-)

RefSeq WP_004454617.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359833Run 6 · HK · 9 sequences
Representative sequenceGCF_000449065#QCK_RS13580Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359833

Simplified PFAM architecture for HKOC_1359833

PFAM domain coverage: 191 / 529 aa (36.1%)

1 aa529 aa
HAMP: 254-294 aaHAMPHisKA: 309-374 aaHisKAHATPase_c: 426-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
  • Domain count: 3
  • Matched identifier: HKOC_1359833
  • Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449065#QCK_RS13580

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 9 over 9 total members. Page 1 / 1.

GCF_000449065#QCK_RS13580 (representative)
QCK_RS13580 · HK · Classic
RefSeq: WP_042743945.1
GCF_006380955#DA423_RS13415
DA423_RS13415 · HK · Classic
RefSeq: WP_042743945.1
GCF_019427905#K1N58_RS10950
K1N58_RS10950 · HK · Classic
RefSeq: WP_042743945.1
GCF_019428005#K1N60_RS05570
K1N60_RS05570 · HK · Classic
RefSeq: WP_042743945.1
GCF_028596425#PSM54_RS03600
PSM54_RS03600 · HK · Classic
RefSeq: WP_042743945.1
GCF_030251025#QQO53_RS16805
QQO53_RS16805 · HK · Classic
RefSeq: WP_334306056.1
GCF_900096205#DK474_RS02655
DK474_RS02655 · HK · Classic
RefSeq: WP_042743945.1
GCF_900164825#B2A67_RS08895
B2A67_RS08895 · HK · Classic
RefSeq: WP_042743945.1
GCF_900166215#B2A33_RS00260
B2A33_RS00260 · HK · Classic
RefSeq: WP_042743945.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096205
AssemblyASM90009620v1 · Scaffoldhaploid
Genome composition4 419 398 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key