Gene detail

DK481_RS10870

Histidine kinase, Classic

Clostridioides difficile · GCF_900096165

ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096165#DK481_RS10870Stable P2CS identifier used across views.
GenomeGCF_900096165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2082201Run 6 · 595 sequences · id 100% · cov 80%
External referencesWP_009889841.1 · Q187J0 · MIST4 DK481_RS10870RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
HAMP: 144-211 aa (68 aa)1HisKA: 232-296 aa (65 aa)2HATPase_c: 342-419 aa (78 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw tokenHAMP:144:0.000000211:211:68:69
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw tokenHisKA:232:0.0000048:296:65:64
3 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw tokenHATPase_c:342:0.00000544:419:90:109
  • Raw architecture: HAMP:144:0.000000211:211:68:69#HisKA:232:0.0000048:296:65:64#HATPase_c:342:0.00000544:419:90:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096165::NZ_FMLW01000008.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span107340-109309Genomic interval covered by the local TCS group.
Context group IDGCF_900096165::NZ_FMLW01000008.1::G00038
Context members
DK481_RS10870DK481_RS10875
Partner locus tags
DK481_RS10870DK481_RS10875
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889841.1Primary protein accession used for annex mappings.
UniProt accessionQ187J0Primary UniProt accession resolved in the annex database.
UniProt IDQ187J0_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK481_RS10870Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMLW01000008.1Sequence record reported by the local genomic context database.
Genomic interval107 340-108 659 nt1 320 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span107 340-109 309 ntGCF_900096165::NZ_FMLW01000008.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096165::NZ_FMLW01000008.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMLW01000008.1All displayed genes belong to this local TCS context.
Neighborhood span107 340-109 309 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
107 340 nt109 309 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK481_RS10875GCF_900096165#DK481_RS10875
RROmpR

108 656-109 309 nt · Reverse (-)

RefSeq WP_009889840.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082201Run 6 · HK · 595 sequences
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082201

Simplified PFAM architecture for HKOC_2082201

PFAM domain coverage: 143 / 439 aa (32.6%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-420 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-420]
  • Domain count: 2
  • Matched identifier: HKOC_2082201
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0217010

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096165
AssemblyASM90009616v1 · Scaffoldhaploid
Genome composition4 104 398 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key