Gene detail

DK481_RS00400

Histidine kinase, Classic

Clostridioides difficile · GCF_900096165

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096165#DK481_RS00400Stable P2CS identifier used across views.
GenomeGCF_900096165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1726898Run 6 · 387 sequences · id 100% · cov 80%
External referencesWP_009889869.1 · A0A0H3N7P5 · MIST4 DK481_RS00400RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DK481_RS00400
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.49e-36:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.45e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.000000106:467:114:109
  • Raw architecture: H_kinase_N:12:1.49e-36:142:132:139#HisKA_2:276:2.45e-16:350:76:76#HATPase_c:370:0.000000106:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096165::NZ_FMLW01000001.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span80297-82274Genomic interval covered by the local TCS group.
Context group IDGCF_900096165::NZ_FMLW01000001.1::G00023
Context members
DK481_RS00400DK481_RS00405
Partner locus tags
DK481_RS00400DK481_RS00405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889869.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N7P5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N7P5_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK481_RS00400Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMLW01000001.1Sequence record reported by the local genomic context database.
Genomic interval80 297-81 706 nt1 410 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span80 297-82 274 ntGCF_900096165::NZ_FMLW01000001.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096165::NZ_FMLW01000001.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMLW01000001.1All displayed genes belong to this local TCS context.
Neighborhood span80 297-82 274 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
80 297 nt82 274 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK481_RS00405GCF_900096165#DK481_RS00405
RRAmiR_NasR

81 699-82 274 nt · Reverse (-)

RefSeq WP_003423977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1726898Run 6 · HK · 387 sequences
Representative sequenceGCF_000003215#QAC_RS0209635Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1726898

Simplified PFAM architecture for HKOC_1726898

PFAM domain coverage: 302 / 469 aa (64.4%)

1 aa469 aa
GAF_PdtaS: 6-141 aaGAF_PdtaSHisKA_2: 276-347 aaHisKA_2HATPase_c: 373-466 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
  • Domain count: 3
  • Matched identifier: HKOC_1726898
  • Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096165
AssemblyASM90009616v1 · Scaffoldhaploid
Genome composition4 104 398 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key