Gene detail

DK481_RS00150

Histidine kinase, Classic

Clostridioides difficile · GCF_900096165

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096165#DK481_RS00150Stable P2CS identifier used across views.
GenomeGCF_900096165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2884661Run 6 · 349 sequences · id 100% · cov 80%
External referencesWP_009893352.1 · A0A0H3NC53 · MIST4 DK481_RS00150RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 196-295 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.0000000829:144:63:64
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw tokenHATPase_c:196:2.42e-22:295:100:109
  • Raw architecture: HisKA:82:0.0000000829:144:63:64#HATPase_c:196:2.42e-22:295:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096165::NZ_FMLW01000001.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30346-31927Genomic interval covered by the local TCS group.
Context group IDGCF_900096165::NZ_FMLW01000001.1::G00021
Context members
DK481_RS00145DK481_RS00150
Partner locus tags
DK481_RS00145DK481_RS00150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893352.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NC53Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NC53_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK481_RS00150Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMLW01000001.1Sequence record reported by the local genomic context database.
Genomic interval31 019-31 927 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 346-31 927 ntGCF_900096165::NZ_FMLW01000001.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096165::NZ_FMLW01000001.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMLW01000001.1All displayed genes belong to this local TCS context.
Neighborhood span30 346-31 927 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 346 nt31 927 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK481_RS00145GCF_900096165#DK481_RS00145
RROmpR

30 346-31 017 nt · Forward (+)

RefSeq WP_009889923.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2884661Run 6 · HK · 349 sequences
Representative sequenceGCF_000003215#QAC_RS0209885Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2884661

Simplified PFAM architecture for HKOC_2884661

PFAM domain coverage: 165 / 302 aa (54.6%)

1 aa302 aa
HisKA: 82-144 aaHisKAHATPase_c: 195-296 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[82-144] | HATPase_c[195-296]
  • Domain count: 2
  • Matched identifier: HKOC_2884661
  • Positioned domains: HisKA 82-144 ; HATPase_c 195-296
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209885

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096165
AssemblyASM90009616v1 · Scaffoldhaploid
Genome composition4 104 398 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key