Gene detail

DK464_RS17565

Histidine kinase, Classic

Clostridioides difficile · GCF_900096045

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096045#DK464_RS17565Stable P2CS identifier used across views.
GenomeGCF_900096045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550383Run 6 · 38 sequences · id 100% · cov 80%
External referencesWP_032547305.1 · MIST4 DK464_RS17565RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage149 / 387 aa (38.5%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-251 aa (64 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-251 aa · 64 aa · 16.5% of protein
Raw tokenHisKA_3:188:4.53e-20:251:65:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.000000000106:378:104:109
  • Raw architecture: HisKA_3:188:4.53e-20:251:65:68#HATPase_c:294:0.000000000106:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096045::NZ_FMLM01000031.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11660-13463Genomic interval covered by the local TCS group.
Context group IDGCF_900096045::NZ_FMLM01000031.1::G00050
Context members
DK464_RS17560DK464_RS17565
Partner locus tags
DK464_RS17560DK464_RS17565
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032547305.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK464_RS17565Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMLM01000031.1Sequence record reported by the local genomic context database.
Genomic interval12 300-13 463 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 660-13 463 ntGCF_900096045::NZ_FMLM01000031.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096045::NZ_FMLM01000031.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMLM01000031.1All displayed genes belong to this local TCS context.
Neighborhood span11 660-13 463 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 660 nt13 463 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK464_RS17560GCF_900096045#DK464_RS17560
RRNarL

11 660-12 307 nt · Reverse (-)

RefSeq WP_021375036.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550383Run 6 · HK · 38 sequences
Representative sequenceGCF_000449185#QCW_RS06390Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550383

Simplified PFAM architecture for HKOC_2550383

PFAM domain coverage: 149 / 387 aa (38.5%)

1 aa387 aa
HisKA_3: 188-251 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-251] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550383
  • Positioned domains: HisKA_3 188-251 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS06390

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096045
AssemblyASM90009604v1 · Scaffoldhaploid
Genome composition4 085 831 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 42 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key