Gene detail

DK464_RS01230

Histidine kinase, Classic

Clostridioides difficile · GCF_900096045

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900096045#DK464_RS01230Stable P2CS identifier used across views.
GenomeGCF_900096045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2682290Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_109277295.1 · MIST4 DK464_RS01230RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.0000000000000795:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:3.82e-25:368:110:109
  • Raw architecture: HisKA:148:0.0000000000000795:211:64:64#HATPase_c:260:3.82e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900096045::NZ_FMLM01000001.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span277033-278882Genomic interval covered by the local TCS group.
Context group IDGCF_900096045::NZ_FMLM01000001.1::G00015
Context members
DK464_RS01230DK464_RS01235
Partner locus tags
DK464_RS01230DK464_RS01235
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_109277295.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDK464_RS01230Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FMLM01000001.1Sequence record reported by the local genomic context database.
Genomic interval277 033-278 148 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span277 033-278 882 ntGCF_900096045::NZ_FMLM01000001.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900096045::NZ_FMLM01000001.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMLM01000001.1All displayed genes belong to this local TCS context.
Neighborhood span277 033-278 882 nt1 850 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
277 033 nt278 882 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DK464_RS01235GCF_900096045#DK464_RS01235
RROmpR

278 184-278 882 nt · Reverse (-)

RefSeq WP_021376496.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2682290Run 6 · HK · 1 sequences
Representative sequenceGCF_900096045#DK464_RS01230The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2682290

Simplified PFAM architecture for HKOC_2682290

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2682290
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_900096045#DK464_RS01230

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900096045
AssemblyASM90009604v1 · Scaffoldhaploid
Genome composition4 085 831 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 42 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key