1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw token
HisKA:94:0.000000109:156:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C4S23_RS08250
Histidine kinase, Classic
Clostridioides difficile · GCF_900015935
ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900015935#C4S23_RS08250Stable P2CS identifier used across views.
GenomeGCF_900015935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw token
HATPase_c:204:2.61e-30:310:107:109- Raw architecture: HisKA:94:0.000000109:156:63:64#HATPase_c:204:2.61e-30:310:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900015935::NZ_FANK01000017.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span61408-63032Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_900015935::NZ_FANK01000017.1::G00035Context members
C4S23_RS08250C4S23_RS08255
Partner locus tags
C4S23_RS08250C4S23_RS08255
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_012816055.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4S2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4S2_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC4S23_RS08250Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FANK01000017.1Sequence record reported by the local genomic context database.
Genomic interval61 408-62 343 nt936 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span61 408-63 032 ntGCF_900015935::NZ_FANK01000017.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900015935::NZ_FANK01000017.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FANK01000017.1All displayed genes belong to this local TCS context.
Neighborhood span61 408-63 032 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
61 408 nt63 032 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C4S23_RS08250GCF_900015935#C4S23_RS08250
HKClassicCurrent focus
61 408-62 343 nt · Reverse (-)
C4S23_RS08255GCF_900015935#C4S23_RS08255
RROmpR
62 340-63 032 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0204275Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2876366
Simplified PFAM architecture for HKOC_2876366
PFAM domain coverage: 170 / 311 aa (54.7%)
1 aa311 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[93-155] | HATPase_c[204-310]
- Domain count: 2
- Matched identifier: HKOC_2876366
- Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0204275
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900015935
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 118 089 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key