Gene detail

A4020_RS17475

Histidine kinase, Classic

Clostridioides difficile · GCF_900014225

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900014225#A4020_RS17475Stable P2CS identifier used across views.
GenomeGCF_900014225Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0388008Run 6 · 8 sequences · id 100% · cov 80%
External referencesWP_065977589.1 · MIST4 A4020_RS17475RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_8HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 912 aa (24.3%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_8: 532-569 aa (38 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 774-885 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS_8#1
532-569 aa · 38 aa · 4.2% of protein
Raw tokenPAS_8:532:0.0000846:569:38:65
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000209:726:72:64
3 HATPase_c#3
774-885 aa · 112 aa · 12.3% of protein
Raw tokenHATPase_c:774:3.22e-25:885:112:109
  • Raw architecture: PAS_8:532:0.0000846:569:38:65#HisKA:655:0.00000000209:726:72:64#HATPase_c:774:3.22e-25:885:112:109
  • Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900014225::NZ_FAAJ01000044.1::G00052
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span21524-24262Genomic interval covered by the local TCS group.
Context group IDGCF_900014225::NZ_FAAJ01000044.1::G00052
Context members
A4020_RS17475
Partner locus tags
A4020_RS17475
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_065977589.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4020_RS17475Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAAJ01000044.1Sequence record reported by the local genomic context database.
Genomic interval21 524-24 262 nt2 739 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span21 524-24 262 ntGCF_900014225::NZ_FAAJ01000044.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900014225::NZ_FAAJ01000044.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAAJ01000044.1All displayed genes belong to this local TCS context.
Neighborhood span21 524-24 262 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 524 nt24 262 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0388008Run 6 · HK · 8 sequences
Representative sequenceGCF_001704795#DCQ01_RS13180Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0388008

Simplified PFAM architecture for HKOC_0388008

PFAM domain coverage: 221 / 912 aa (24.2%)

1 aa912 aa
PAS_8: 532-572 aaHisKA: 656-724 aaHisKAHATPase_c: 774-884 aaHATPase_c
PAS_8HisKAHATPase_c
  • Simplified architecture: PAS_8 + HisKA + HATPase_c
  • Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
  • Domain count: 3
  • Matched identifier: HKOC_0388008
  • Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Visualization

Representative gene: GCF_001704795#DCQ01_RS13180

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900014225
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 068 388 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 42 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key