Gene detail

A4Y25_RS08705

Histidine kinase, Classic

Clostridioides difficile · GCF_900013115

ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900013115#A4Y25_RS08705Stable P2CS identifier used across views.
GenomeGCF_900013115Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2362318Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_074048395.1 · MIST4 A4Y25_RS08705RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
HisKA: 185-250 aa (66 aa)1HATPase_c: 296-408 aa (113 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw tokenHisKA:185:0.000000000159:250:66:64
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw tokenHATPase_c:296:7.73e-25:408:113:109
  • Raw architecture: HisKA:185:0.000000000159:250:66:64#HATPase_c:296:7.73e-25:408:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900013115::NZ_FAFF01000009.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span26412-28305Genomic interval covered by the local TCS group.
Context group IDGCF_900013115::NZ_FAFF01000009.1::G00034
Context members
A4Y25_RS08705A4Y25_RS08710
Partner locus tags
A4Y25_RS08705A4Y25_RS08710
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074048395.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Y25_RS08705Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAFF01000009.1Sequence record reported by the local genomic context database.
Genomic interval26 412-27 644 nt1 233 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span26 412-28 305 ntGCF_900013115::NZ_FAFF01000009.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900013115::NZ_FAFF01000009.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAFF01000009.1All displayed genes belong to this local TCS context.
Neighborhood span26 412-28 305 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 412 nt28 305 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4Y25_RS08710GCF_900013115#A4Y25_RS08710
RROmpR

27 634-28 305 nt · Reverse (-)

RefSeq WP_021360572.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2362318Run 6 · HK · 1 sequences
Representative sequenceGCF_900013115#A4Y25_RS08705The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2362318

Simplified PFAM architecture for HKOC_2362318

PFAM domain coverage: 177 / 410 aa (43.2%)

1 aa410 aa
HisKA: 185-250 aaHisKAHATPase_c: 297-407 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[185-250] | HATPase_c[297-407]
  • Domain count: 2
  • Matched identifier: HKOC_2362318
  • Positioned domains: HisKA 185-250 ; HATPase_c 297-407
Cluster members and taxonomy
Visualization

Representative gene: GCF_900013115#A4Y25_RS08705

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900013115
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 123 326 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key