Gene detail

A4Z85_RS00835

Histidine kinase, Classic

Clostridioides difficile · GCF_900011895

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900011895#A4Z85_RS00835Stable P2CS identifier used across views.
GenomeGCF_900011895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0801760Run 6 · 21 sequences · id 100% · cov 80%
External referencesWP_175345182.1 · MIST4 A4Z85_RS00835RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for A4Z85_RS00835
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000197:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000197:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000197:524:68:64#HATPase_c:570:0.00000000000197:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900011895::NZ_CZZI01000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span168789-171737Genomic interval covered by the local TCS group.
Context group IDGCF_900011895::NZ_CZZI01000001.1::G00003
Context members
A4Z85_RS00825A4Z85_RS00835
Partner locus tags
A4Z85_RS00825A4Z85_RS00835
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_175345182.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Z85_RS00835Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CZZI01000001.1Sequence record reported by the local genomic context database.
Genomic interval169 677-171 737 nt2 061 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span168 789-171 737 ntGCF_900011895::NZ_CZZI01000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900011895::NZ_CZZI01000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CZZI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span168 789-171 737 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
168 789 nt171 737 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4Z85_RS00825GCF_900011895#A4Z85_RS00825
RROmpR

168 789-169 481 nt · Forward (+)

RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0801760Run 6 · HK · 21 sequences
Representative sequenceGCF_009867095#DF008_RS07855Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0801760

Simplified PFAM architecture for HKOC_0801760

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0801760
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_009867095#DF008_RS07855

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900011895
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 141 352 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key