Gene detail

A4Y63_RS17195

Histidine kinase, Classic

Clostridioides difficile · GCF_900010935

ClassHKTypeClassicLength328 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900010935#A4Y63_RS17195Stable P2CS identifier used across views.
GenomeGCF_900010935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550381Run 6 · 61 sequences · id 100% · cov 80%
External referencesWP_074089697.1 · MIST4 A4Y63_RS17195RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length328 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 328 aa (46.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa328 aa
HisKA_3: 129-194 aa (66 aa)1HATPase_c: 235-319 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
129-194 aa · 66 aa · 20.1% of protein
Raw tokenHisKA_3:129:5.58e-20:194:67:68
2 HATPase_c#2
235-319 aa · 85 aa · 25.9% of protein
Raw tokenHATPase_c:235:0.000000000158:319:104:109
  • Raw architecture: HisKA_3:129:5.58e-20:194:67:68#HATPase_c:235:0.000000000158:319:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900010935::NZ_FAGF01000085.1::G00051
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11363-12990Genomic interval covered by the local TCS group.
Context group IDGCF_900010935::NZ_FAGF01000085.1::G00051
Context members
A4Y63_RS17190A4Y63_RS17195
Partner locus tags
A4Y63_RS17190A4Y63_RS17195
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074089697.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Y63_RS17195Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAGF01000085.1Sequence record reported by the local genomic context database.
Genomic interval12 003-12 990 nt988 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 363-12 990 ntGCF_900010935::NZ_FAGF01000085.1::G00051

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900010935::NZ_FAGF01000085.1::G00051

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAGF01000085.1All displayed genes belong to this local TCS context.
Neighborhood span11 363-12 990 nt1 628 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 363 nt12 990 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4Y63_RS17190GCF_900010935#A4Y63_RS17190
RRNarL

11 363-12 010 nt · Reverse (-)

RefSeq WP_009896181.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550381Run 6 · HK · 61 sequences
Representative sequenceGCF_000448845#QAQ_RS06320Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550381

Simplified PFAM architecture for HKOC_2550381

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550381
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448845#QAQ_RS06320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900010935
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 098 661 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key