Gene detail

A4Y63_RS00635

Histidine kinase, Classic

Clostridioides difficile · GCF_900010935

ClassHKTypeClassicLength454 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900010935#A4Y63_RS00635Stable P2CS identifier used across views.
GenomeGCF_900010935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1914581Run 6 · 34 sequences · id 100% · cov 80%
External referencesWP_054352301.1 · MIST4 A4Y63_RS00635RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length454 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 454 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for A4Y63_RS00635
Domain-by-domain annotation2 items
1 HisKA#1
234-299 aa · 66 aa · 14.5% of protein
Raw tokenHisKA:234:0.00000000000000206:299:66:64
2 HATPase_c#2
344-454 aa · 111 aa · 24.4% of protein
Raw tokenHATPase_c:344:8.76e-22:454:111:109
  • Raw architecture: HisKA:234:0.00000000000000206:299:66:64#HATPase_c:344:8.76e-22:454:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900010935::NZ_FAGF01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span154934-156948Genomic interval covered by the local TCS group.
Context group IDGCF_900010935::NZ_FAGF01000001.1::G00002
Context members
A4Y63_RS00635A4Y63_RS00640
Partner locus tags
A4Y63_RS00635A4Y63_RS00640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_054352301.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Y63_RS00635Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAGF01000001.1Sequence record reported by the local genomic context database.
Genomic interval154 934-156 298 nt1 365 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span154 934-156 948 ntGCF_900010935::NZ_FAGF01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900010935::NZ_FAGF01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAGF01000001.1All displayed genes belong to this local TCS context.
Neighborhood span154 934-156 948 nt2 015 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
154 934 nt156 948 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4Y63_RS00640GCF_900010935#A4Y63_RS00640
RROmpR

156 289-156 948 nt · Reverse (-)

RefSeq WP_021404737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1914581Run 6 · HK · 34 sequences
Representative sequenceGCF_002865355#CDL25_RS15320Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1914581

Simplified PFAM architecture for HKOC_1914581

PFAM domain coverage: 177 / 454 aa (39.0%)

1 aa454 aa
HisKA: 234-299 aaHisKAHATPase_c: 344-454 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[234-299] | HATPase_c[344-454]
  • Domain count: 2
  • Matched identifier: HKOC_1914581
  • Positioned domains: HisKA 234-299 ; HATPase_c 344-454
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865355#CDL25_RS15320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900010935
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 098 661 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key