Gene detail

A4Z38_RS18175

Histidine kinase, Classic

Clostridioides difficile · GCF_900009415

ClassHKTypeClassicLength293 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900009415#A4Z38_RS18175Stable P2CS identifier used across views.
GenomeGCF_900009415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2893822Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_074091118.1 · MIST4 A4Z38_RS18175RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length293 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 293 aa (51.5%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa293 aa
HisKA_3: 94-159 aa (66 aa)1HATPase_c: 200-284 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
94-159 aa · 66 aa · 22.5% of protein
Raw tokenHisKA_3:94:1.26e-19:159:67:68
2 HATPase_c#2
200-284 aa · 85 aa · 29.0% of protein
Raw tokenHATPase_c:200:0.000000000117:284:104:109
  • Raw architecture: HisKA_3:94:1.26e-19:159:67:68#HATPase_c:200:0.000000000117:284:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900009415::NZ_FAAG01000055.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-1523Genomic interval covered by the local TCS group.
Context group IDGCF_900009415::NZ_FAAG01000055.1::G00052
Context members
A4Z38_RS18175A4Z38_RS18180
Partner locus tags
A4Z38_RS18175A4Z38_RS18180
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074091118.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Z38_RS18175Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAAG01000055.1Sequence record reported by the local genomic context database.
Genomic interval1-883 nt883 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 523 ntGCF_900009415::NZ_FAAG01000055.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900009415::NZ_FAAG01000055.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAAG01000055.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 523 nt1 523 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 523 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2893822Run 6 · HK · 1 sequences
Representative sequenceGCF_900009415#A4Z38_RS18175The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2893822

Simplified PFAM architecture for HKOC_2893822

PFAM domain coverage: 150 / 293 aa (51.2%)

1 aa293 aa
HisKA_3: 94-158 aaHisKA_3HATPase_c: 200-284 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[94-158] | HATPase_c[200-284]
  • Domain count: 2
  • Matched identifier: HKOC_2893822
  • Positioned domains: HisKA_3 94-158 ; HATPase_c 200-284
Cluster members and taxonomy
Visualization

Representative gene: GCF_900009415#A4Z38_RS18175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900009415
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 120 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key