Gene detail

A4X89_RS04155

Histidine kinase, Classic

Clostridioides difficile · GCF_900008785

ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900008785#A4X89_RS04155Stable P2CS identifier used across views.
GenomeGCF_900008785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1472479Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_074080496.1 · MIST4 A4X89_RS04155RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
His_kinase: 305-376 aa (72 aa)1HATPase_c: 396-496 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw tokenHis_kinase:305:1.17e-24:376:72:80
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw tokenHATPase_c:396:0.00000283:496:107:109
  • Raw architecture: His_kinase:305:1.17e-24:376:72:80#HATPase_c:396:0.00000283:496:107:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900008785::NZ_FAJB01000003.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span153664-155981Genomic interval covered by the local TCS group.
Context group IDGCF_900008785::NZ_FAJB01000003.1::G00011
Context members
A4X89_RS04155A4X89_RS04160
Partner locus tags
A4X89_RS04155A4X89_RS04160
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074080496.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4X89_RS04155Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAJB01000003.1Sequence record reported by the local genomic context database.
Genomic interval153 664-155 169 nt1 506 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span153 664-155 981 ntGCF_900008785::NZ_FAJB01000003.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900008785::NZ_FAJB01000003.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAJB01000003.1All displayed genes belong to this local TCS context.
Neighborhood span153 664-155 981 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
153 664 nt155 981 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4X89_RS04160GCF_900008785#A4X89_RS04160
RRunclassified

155 283-155 981 nt · Forward (+)

RefSeq WP_003436119.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1472479Run 6 · HK · 6 sequences
Representative sequenceGCF_032081295#XC29_RS13405Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1472479

Simplified PFAM architecture for HKOC_1472479

PFAM domain coverage: 137 / 501 aa (27.3%)

1 aa501 aa
Cupin_2: 34-96 aaCupin_2His_kinase: 303-376 aaHis_kinase
Cupin_2His_kinase
  • Simplified architecture: Cupin_2 + His_kinase
  • Raw architecture: Cupin_2[34-96] | His_kinase[303-376]
  • Domain count: 2
  • Matched identifier: HKOC_1472479
  • Positioned domains: Cupin_2 34-96 ; His_kinase 303-376
Cluster members and taxonomy
Visualization

Representative gene: GCF_032081295#XC29_RS13405

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900008785
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 169 839 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 45 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key