1 HAMP#1
46-115 aa · 70 aa · 19.4% of protein
Raw token
HAMP:46:0.0000000000146:115:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACH0RF_RS07945
Histidine kinase, Classic
Clostridioides difficile · GCF_043845185
ClassHKTypeClassicLength361 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_043845185#ACH0RF_RS07945Stable P2CS identifier used across views.
GenomeGCF_043845185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length361 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 361 aa (66.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa361 aa
Domain-by-domain annotation3 items
2 HisKA#2
140-204 aa · 65 aa · 18.0% of protein
Raw token
HisKA:140:0.0000000000538:204:65:643 HATPase_c#3
250-353 aa · 104 aa · 28.8% of protein
Raw token
HATPase_c:250:5.08e-19:353:108:109- Raw architecture: HAMP:46:0.0000000000146:115:70:69#HisKA:140:0.0000000000538:204:65:64#HATPase_c:250:5.08e-19:353:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_043845185::NZ_JBAMGH010000004.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span184118-186152Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_043845185::NZ_JBAMGH010000004.1::G00025Context members
ACH0RF_RS07945ACH0RF_RS07950
Partner locus tags
ACH0RF_RS07945ACH0RF_RS07950
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_262805522.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACH0RF_RS07945Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JBAMGH010000004.1Sequence record reported by the local genomic context database.
Genomic interval184 118-185 203 nt1 086 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span184 118-186 152 ntGCF_043845185::NZ_JBAMGH010000004.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_043845185::NZ_JBAMGH010000004.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBAMGH010000004.1All displayed genes belong to this local TCS context.
Neighborhood span184 118-186 152 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
184 118 nt186 152 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACH0RF_RS07945GCF_043845185#ACH0RF_RS07945
HKClassicCurrent focus
184 118-185 203 nt · Reverse (-)
ACH0RF_RS07950GCF_043845185#ACH0RF_RS07950
RROmpR
185 481-186 152 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_025533055#H3U22_RS14150Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2744291
Simplified PFAM architecture for HKOC_2744291
PFAM domain coverage: 217 / 361 aa (60.1%)
1 aa361 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[65-114] | HisKA[141-204] | HATPase_c[251-353]
- Domain count: 3
- Matched identifier: HKOC_2744291
- Positioned domains: HAMP 65-114 ; HisKA 141-204 ; HATPase_c 251-353
Cluster members and taxonomy
Representative gene: GCF_025533055#H3U22_RS14150
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_043845185
AssemblyASM4384518v1 · Scaffoldhaploid
Genome composition4 360 383 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key