Gene detail

ACGAK6_RS02355

Response regulator NtrC family

Clostridioides difficile · GCF_043107665

ClassRRTypeNtrCLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_043107665#ACGAK6_RS02355Stable P2CS identifier used across views.
GenomeGCF_043107665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0335104Run 7 · 25 sequences · id 100% · cov 80%
External referencesWP_074033735.1 · MIST4 ACGAK6_RS02355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 440 aa (61.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Response_reg: 3-114 aa (112 aa)1AAA_5: 157-275 aa (119 aa)2HTH_8: 398-437 aa (40 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
3-114 aa · 112 aa · 25.5% of protein
Raw tokenResponse_reg:3:9.73e-26:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 27.0% of protein
Raw tokenAAA_5:157:0.00000000272:275:128:135
3 HTH_8#3
398-437 aa · 40 aa · 9.1% of protein
Raw tokenHTH_8:398:0.000000000186:437:40:40
  • Raw architecture: Response_reg:3:9.73e-26:114:112:111#AAA_5:157:0.00000000272:275:128:135#HTH_8:398:0.000000000186:437:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_043107665::NZ_JBICPH010000001.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span501176-504492Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACGAK6_02355RefSeq proteinWP_074033735.1
Context group IDGCF_043107665::NZ_JBICPH010000001.1::G00022
Context members
ACGAK6_RS02355ACGAK6_RS02360
Partner locus tags
ACGAK6_RS02355ACGAK6_RS02360
Partner old locus tags
ACGAK6_02355ACGAK6_02360
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074033735.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACGAK6_RS02355Primary locus identifier stored in the genes table.
Old locus tagACGAK6_02355Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBICPH010000001.1Sequence record reported by the local genomic context database.
Genomic interval501 176-502 498 nt1 323 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span501 176-504 492 ntGCF_043107665::NZ_JBICPH010000001.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_043107665::NZ_JBICPH010000001.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBICPH010000001.1All displayed genes belong to this local TCS context.
Neighborhood span501 176-504 492 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
501 176 nt504 492 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACGAK6_RS02355GCF_043107665#ACGAK6_RS02355
RRNtrCCurrent focus

501 176-502 498 nt · Reverse (-)

Old locus ACGAK6_02355RefSeq WP_074033735.1
ACGAK6_RS02360GCF_043107665#ACGAK6_RS02360
HKClassic

502 498-504 492 nt · Reverse (-)

Old locus ACGAK6_02360RefSeq WP_011861320.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0335104Run 7 · RR · 25 sequences
Representative sequenceGCF_025532245#J4G21_RS17915Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0335104

Simplified PFAM architecture for RROC_0335104

PFAM domain coverage: 386 / 440 aa (87.7%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regSigma54_activat: 137-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[137-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0335104
  • Positioned domains: Response_reg 3-113 ; Sigma54_activat 137-300 ; AAA_lid_14 306-375 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_025532245#J4G21_RS17915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_043107665
AssemblyASM4310766v1 · Contighaploid
Genome composition4 218 961 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key