1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000611:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACGAKA_RS08040
Histidine kinase, Classic
Clostridioides difficile · GCF_043107645
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_043107645#ACGAKA_RS08040Stable P2CS identifier used across views.
GenomeGCF_043107645Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:1e-28:668:104:109- Raw architecture: HisKA:449:0.00000000611:514:66:64#HATPase_c:565:1e-28:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_043107645::NZ_JBICPF010000005.1::G00049
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span126690-132414Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACGAKA_08045RefSeq proteinWP_021427717.1
Context group ID
GCF_043107645::NZ_JBICPF010000005.1::G00049Context members
ACGAKA_RS08035ACGAKA_RS08040ACGAKA_RS08045ACGAKA_RS08050ACGAKA_RS08055
Partner locus tags
ACGAKA_RS08035ACGAKA_RS08040ACGAKA_RS08045ACGAKA_RS08050ACGAKA_RS08055
Partner old locus tags
ACGAKA_08040ACGAKA_08045ACGAKA_08050ACGAKA_08055ACGAKA_08060
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021427717.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DA33Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DA33_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACGAKA_RS08040Primary locus identifier stored in the genes table.
Old locus tagACGAKA_08045Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBICPF010000005.1Sequence record reported by the local genomic context database.
Genomic interval127 439-129 454 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span126 690-132 414 ntGCF_043107645::NZ_JBICPF010000005.1::G00049
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_043107645::NZ_JBICPF010000005.1::G00049Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBICPF010000005.1All displayed genes belong to this local TCS context.
Neighborhood span126 690-132 414 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
126 690 nt132 414 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
ACGAKA_RS08035GCF_043107645#ACGAKA_RS08035
RROmpR
126 690-127 367 nt · Forward (+)
ACGAKA_RS08040GCF_043107645#ACGAKA_RS08040
HKClassicCurrent focus
127 439-129 454 nt · Forward (+)
ACGAKA_RS08045GCF_043107645#ACGAKA_RS08045
RROmpR
129 504-130 184 nt · Forward (+)
ACGAKA_RS08050GCF_043107645#ACGAKA_RS08050
RROmpR
130 565-131 263 nt · Forward (+)
ACGAKA_RS08055GCF_043107645#ACGAKA_RS08055
HKClassic
131 299-132 414 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS16915Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842488
Simplified PFAM architecture for HKOC_0842488
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842488
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS16915
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_043107645
AssemblyASM4310764v1 · Contighaploid
Genome composition4 061 598 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key