1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw token
HisKA:182:0.00000000000000837:240:59:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACGAK2_RS12255
Histidine kinase, Classic
Clostridioides difficile · GCF_043107465
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_043107465#ACGAK2_RS12255Stable P2CS identifier used across views.
GenomeGCF_043107465Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw token
HATPase_c:293:1.2e-18:391:100:109- Raw architecture: HisKA:182:0.00000000000000837:240:59:64#HATPase_c:293:1.2e-18:391:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_043107465::NZ_JBICPB010000010.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36863-38706Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACGAK2_12295RefSeq proteinWP_011860822.1
Context group ID
GCF_043107465::NZ_JBICPB010000010.1::G00003Context members
ACGAK2_RS12250ACGAK2_RS12255
Partner locus tags
ACGAK2_RS12250ACGAK2_RS12255
Partner old locus tags
ACGAK2_12290ACGAK2_12295
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011860822.1Primary protein accession used for annex mappings.
UniProt accessionQ188Q5Primary UniProt accession resolved in the annex database.
UniProt IDQ188Q5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACGAK2_RS12255Primary locus identifier stored in the genes table.
Old locus tagACGAK2_12295Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBICPB010000010.1Sequence record reported by the local genomic context database.
Genomic interval37 525-38 706 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span36 863-38 706 ntGCF_043107465::NZ_JBICPB010000010.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_043107465::NZ_JBICPB010000010.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBICPB010000010.1All displayed genes belong to this local TCS context.
Neighborhood span36 863-38 706 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 863 nt38 706 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACGAK2_RS12250GCF_043107465#ACGAK2_RS12250
RROmpR
36 863-37 525 nt · Forward (+)
ACGAK2_RS12255GCF_043107465#ACGAK2_RS12255
HKClassicCurrent focus
37 525-38 706 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS02855Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503244
Simplified PFAM architecture for HKOC_2503244
PFAM domain coverage: 162 / 393 aa (41.2%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[179-240] | HATPase_c[292-391]
- Domain count: 2
- Matched identifier: HKOC_2503244
- Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS02855
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_043107465
AssemblyASM4310746v1 · Contighaploid
Genome composition4 207 368 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key