Gene detail

ACGAKH_RS07805

Histidine kinase, Classic

Clostridioides difficile · GCF_043107255

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_043107255#ACGAKH_RS07805Stable P2CS identifier used across views.
GenomeGCF_043107255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676168Run 6 · 259 sequences · id 100% · cov 80%
External referencesWP_021388285.1 · A0A9P3YQG4 · MIST4 ACGAKH_RS07805RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.0000000000000679:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:5.15e-25:368:110:109
  • Raw architecture: HisKA:148:0.0000000000000679:211:64:64#HATPase_c:260:5.15e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_043107255::NZ_JBICOV010000005.1::G00044
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span169640-175364Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACGAKH_07805RefSeq proteinWP_021388285.1
Context group IDGCF_043107255::NZ_JBICOV010000005.1::G00044
Context members
ACGAKH_RS07805ACGAKH_RS07810ACGAKH_RS07815ACGAKH_RS07820ACGAKH_RS07825
Partner locus tags
ACGAKH_RS07805ACGAKH_RS07810ACGAKH_RS07815ACGAKH_RS07820ACGAKH_RS07825
Partner old locus tags
ACGAKH_07805ACGAKH_07810ACGAKH_07815ACGAKH_07820ACGAKH_07825

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021388285.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YQG4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YQG4_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACGAKH_RS07805Primary locus identifier stored in the genes table.
Old locus tagACGAKH_07805Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBICOV010000005.1Sequence record reported by the local genomic context database.
Genomic interval169 640-170 755 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span169 640-175 364 ntGCF_043107255::NZ_JBICOV010000005.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_043107255::NZ_JBICOV010000005.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBICOV010000005.1All displayed genes belong to this local TCS context.
Neighborhood span169 640-175 364 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
169 640 nt175 364 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

ACGAKH_RS07805GCF_043107255#ACGAKH_RS07805
HKClassicCurrent focus

169 640-170 755 nt · Reverse (-)

Old locus ACGAKH_07805RefSeq WP_021388285.1
ACGAKH_RS07810GCF_043107255#ACGAKH_RS07810
RROmpR

170 791-171 489 nt · Reverse (-)

Old locus ACGAKH_07810RefSeq WP_003432359.1
ACGAKH_RS07815GCF_043107255#ACGAKH_RS07815
RROmpR

171 870-172 550 nt · Reverse (-)

Old locus ACGAKH_07815RefSeq WP_003432361.1
ACGAKH_RS07820GCF_043107255#ACGAKH_RS07820
HKClassic

172 600-174 615 nt · Reverse (-)

Old locus ACGAKH_07820RefSeq WP_021427717.1
ACGAKH_RS07825GCF_043107255#ACGAKH_RS07825
RROmpR

174 687-175 364 nt · Reverse (-)

Old locus ACGAKH_07825RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676168Run 6 · HK · 259 sequences
Representative sequenceGCF_000210395#CDM68_RS16900Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676168

Simplified PFAM architecture for HKOC_2676168

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676168
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS16900

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_043107255
AssemblyASM4310725v1 · Contighaploid
Genome composition4 213 950 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key