Gene detail

ACFVV6_RS25955

Histidine kinase, Classic

Bacillus mycoides · GCF_042882505

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042882505#ACFVV6_RS25955Stable P2CS identifier used across views.
GenomeGCF_042882505Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1114715Run 6 · 38 sequences · id 100% · cov 80%
External referencesWP_002184458.1 · A0AAP7W5I4 · MIST4 ACFVV6_RS25955RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAF_3His_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage308 / 589 aa (52.3%)Merged over positioned domains only.
Domain description1 GAF_3,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
GAF_3: 237-361 aa (125 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 473-576 aa (104 aa)3
Domain-by-domain annotation3 items
1 GAF_3#1
237-361 aa · 125 aa · 21.2% of protein
Raw tokenGAF_3:237:0.0000000706:361:131:129
2 His_kinase#2
375-453 aa · 79 aa · 13.4% of protein
Raw tokenHis_kinase:375:1.15e-29:453:80:80
3 HATPase_c#3
473-576 aa · 104 aa · 17.7% of protein
Raw tokenHATPase_c:473:0.0000000000031:576:108:109
  • Raw architecture: GAF_3:237:0.0000000706:361:131:129#His_kinase:375:1.15e-29:453:80:80#HATPase_c:473:0.0000000000031:576:108:109
  • Domain description: 1 GAF_3,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_042882505::NZ_JBHVVX010000018.1::G00069
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span57483-59970Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACFVV6_25960RefSeq proteinWP_002184458.1
Context group IDGCF_042882505::NZ_JBHVVX010000018.1::G00069
Context members
ACFVV6_RS25955ACFVV6_RS25960
Partner locus tags
ACFVV6_RS25955ACFVV6_RS25960
Partner old locus tags
ACFVV6_25960ACFVV6_25965
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002184458.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP7W5I4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP7W5I4_BACMYDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACFVV6_RS25955Primary locus identifier stored in the genes table.
Old locus tagACFVV6_25960Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBHVVX010000018.1Sequence record reported by the local genomic context database.
Genomic interval57 483-59 252 nt1 770 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span57 483-59 970 ntGCF_042882505::NZ_JBHVVX010000018.1::G00069

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_042882505::NZ_JBHVVX010000018.1::G00069

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBHVVX010000018.1All displayed genes belong to this local TCS context.
Neighborhood span57 483-59 970 nt2 488 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
57 483 nt59 970 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACFVV6_RS25955GCF_042882505#ACFVV6_RS25955
HKClassicCurrent focus

57 483-59 252 nt · Forward (+)

Old locus ACFVV6_25960RefSeq WP_002184458.1
ACFVV6_RS25960GCF_042882505#ACFVV6_RS25960
RRLytTR

59 230-59 970 nt · Forward (+)

Old locus ACFVV6_25965RefSeq WP_002184460.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1114715Run 6 · HK · 38 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS24580Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + GAF + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1114715

Simplified PFAM architecture for HKOC_1114715

PFAM domain coverage: 483 / 589 aa (82.0%)

1 aa589 aa
5TM-5TMR_LYT: 26-203 aa5TM-5TMR_LYTGAF: 237-359 aaGAFHis_kinase: 375-453 aaHis_kinaseHATPase_c: 473-575 aaHATPase_c
5TM-5TMR_LYTGAFHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + GAF + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[26-203] | GAF[237-359] | His_kinase[375-453] | HATPase_c[473-575]
  • Domain count: 4
  • Matched identifier: HKOC_1114715
  • Positioned domains: 5TM-5TMR_LYT 26-203 ; GAF 237-359 ; His_kinase 375-453 ; HATPase_c 473-575
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS24580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_042882505
AssemblyASM4288250v1 · Scaffoldhaploid
Genome composition5 845 824 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 132 · HK 71 · RR 61CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key