Gene detail

ACFWML_RS22165

Histidine kinase, Classic

Bacillus mycoides · GCF_042722135

ClassHKTypeClassicLength587 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042722135#ACFWML_RS22165Stable P2CS identifier used across views.
GenomeGCF_042722135Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1125685Run 6 · 129 sequences · id 100% · cov 80%
External referencesWP_002167588.1 · R8D160 · MIST4 ACFWML_RS22165RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length587 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 587 aa (80.1%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa587 aa
sCache_like: 35-149 aa (115 aa)1HAMP: 165-234 aa (70 aa)2PAS: 245-351 aa (107 aa)3HisKA: 360-427 aa (68 aa)4HATPase_c: 472-581 aa (110 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-149 aa · 115 aa · 19.6% of protein
Raw tokensCache_like:35:2.42e-26:149:117:114
2 HAMP#2
165-234 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:165:0.00000000000853:234:70:69
3 PAS#3
245-351 aa · 107 aa · 18.2% of protein
Raw tokenPAS:245:0.0000000000000282:351:112:113
4 HisKA#4
360-427 aa · 68 aa · 11.6% of protein
Raw tokenHisKA:360:1.48e-21:427:68:64
5 HATPase_c#5
472-581 aa · 110 aa · 18.7% of protein
Raw tokenHATPase_c:472:7.72e-36:581:110:109
  • Raw architecture: sCache_like:35:2.42e-26:149:117:114#HAMP:165:0.00000000000853:234:70:69#PAS:245:0.0000000000000282:351:112:113#HisKA:360:1.48e-21:427:68:64#HATPase_c:472:7.72e-36:581:110:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_042722135::NZ_JBHXKL010000035.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span44739-47214Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACFWML_22165RefSeq proteinWP_002167588.1
Context group IDGCF_042722135::NZ_JBHXKL010000035.1::G00052
Context members
ACFWML_RS22165ACFWML_RS22170
Partner locus tags
ACFWML_RS22165ACFWML_RS22170
Partner old locus tags
ACFWML_22165ACFWML_22170
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002167588.1Primary protein accession used for annex mappings.
UniProt accessionR8D160Primary UniProt accession resolved in the annex database.
UniProt IDR8D160_BACCEDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACFWML_RS22165Primary locus identifier stored in the genes table.
Old locus tagACFWML_22165Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBHXKL010000035.1Sequence record reported by the local genomic context database.
Genomic interval44 739-46 502 nt1 764 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span44 739-47 214 ntGCF_042722135::NZ_JBHXKL010000035.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_042722135::NZ_JBHXKL010000035.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBHXKL010000035.1All displayed genes belong to this local TCS context.
Neighborhood span44 739-47 214 nt2 476 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
44 739 nt47 214 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACFWML_RS22165GCF_042722135#ACFWML_RS22165
HKClassicCurrent focus

44 739-46 502 nt · Reverse (-)

Old locus ACFWML_22165RefSeq WP_002167588.1
ACFWML_RS22170GCF_042722135#ACFWML_RS22170
RROmpR

46 495-47 214 nt · Reverse (-)

Old locus ACFWML_22170RefSeq WP_002129355.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1125685Run 6 · HK · 129 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS20615Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1125685

Simplified PFAM architecture for HKOC_1125685

PFAM domain coverage: 449 / 587 aa (76.5%)

1 aa587 aa
sCache_like: 33-149 aasCache_likeHAMP: 188-234 aaHAMPPAS: 245-351 aaPASHisKA: 360-426 aaHisKAHATPase_c: 472-582 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-149] | HAMP[188-234] | PAS[245-351] | HisKA[360-426] | HATPase_c[472-582]
  • Domain count: 5
  • Matched identifier: HKOC_1125685
  • Positioned domains: sCache_like 33-149 ; HAMP 188-234 ; PAS 245-351 ; HisKA 360-426 ; HATPase_c 472-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS20615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_042722135
AssemblyASM4272213v1 · Scaffoldhaploid
Genome composition5 830 691 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 132 · HK 71 · RR 61CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key