Gene detail

ACFWML_RS04185

Histidine kinase, Classic

Bacillus mycoides · GCF_042722135

ClassHKTypeClassicLength484 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042722135#ACFWML_RS04185Stable P2CS identifier used across views.
GenomeGCF_042722135Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1584444Run 6 · 37 sequences · id 100% · cov 80%
External referencesWP_016120905.1 · A0AAP8H2M0 · MIST4 ACFWML_RS04185RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length484 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 484 aa (51.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for ACFWML_RS04185
Domain-by-domain annotation3 items
1 HAMP#1
174-243 aa · 70 aa · 14.5% of protein
Raw tokenHAMP:174:7.32e-17:243:70:69
2 HisKA#2
255-319 aa · 65 aa · 13.4% of protein
Raw tokenHisKA:255:3.56e-16:319:65:64
3 HATPase_c#3
367-480 aa · 114 aa · 23.6% of protein
Raw tokenHATPase_c:367:2.22e-30:480:114:109
  • Raw architecture: HAMP:174:7.32e-17:243:70:69#HisKA:255:3.56e-16:319:65:64#HATPase_c:367:2.22e-30:480:114:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_042722135::NZ_JBHXKL010000002.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span72443-74588Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACFWML_04185RefSeq proteinWP_016120905.1
Context group IDGCF_042722135::NZ_JBHXKL010000002.1::G00004
Context members
ACFWML_RS04180ACFWML_RS04185
Partner locus tags
ACFWML_RS04180ACFWML_RS04185
Partner old locus tags
ACFWML_04180ACFWML_04185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_016120905.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP8H2M0Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP8H2M0_BACMYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACFWML_RS04185Primary locus identifier stored in the genes table.
Old locus tagACFWML_04185Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBHXKL010000002.1Sequence record reported by the local genomic context database.
Genomic interval73 134-74 588 nt1 455 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span72 443-74 588 ntGCF_042722135::NZ_JBHXKL010000002.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_042722135::NZ_JBHXKL010000002.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBHXKL010000002.1All displayed genes belong to this local TCS context.
Neighborhood span72 443-74 588 nt2 146 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
72 443 nt74 588 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACFWML_RS04180GCF_042722135#ACFWML_RS04180
RROmpR

72 443-73 132 nt · Reverse (-)

Old locus ACFWML_04180RefSeq WP_003191846.1
ACFWML_RS04185GCF_042722135#ACFWML_RS04185
HKClassicCurrent focus

73 134-74 588 nt · Reverse (-)

Old locus ACFWML_04185RefSeq WP_016120905.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1584444Run 6 · HK · 37 sequences
Representative sequenceGCF_000399425#IK1_RS22555Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1584444

Simplified PFAM architecture for HKOC_1584444

PFAM domain coverage: 227 / 484 aa (46.9%)

1 aa484 aa
HAMP: 191-243 aaHAMPHisKA: 255-319 aaHisKAHATPase_c: 370-478 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[191-243] | HisKA[255-319] | HATPase_c[370-478]
  • Domain count: 3
  • Matched identifier: HKOC_1584444
  • Positioned domains: HAMP 191-243 ; HisKA 255-319 ; HATPase_c 370-478
Cluster members and taxonomy
Visualization

Representative gene: GCF_000399425#IK1_RS22555

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_042722135
AssemblyASM4272213v1 · Scaffoldhaploid
Genome composition5 830 691 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 132 · HK 71 · RR 61CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key