1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw token
His_kinase:305:1.28e-24:376:72:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
R2B51_RS14685
Histidine kinase, Classic
Clostridioides difficile · GCF_042449905
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042449905#R2B51_RS14685Stable P2CS identifier used across views.
GenomeGCF_042449905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 501 aa (33.9%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
396-493 aa · 98 aa · 19.6% of protein
Raw token
HATPase_c:396:0.00000272:493:104:109- Raw architecture: His_kinase:305:1.28e-24:376:72:80#HATPase_c:396:0.00000272:493:104:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_042449905::NZ_CP137339.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3155697-3158014Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_042449905::NZ_CP137339.1::G00044Context members
R2B51_RS14680R2B51_RS14685
Partner locus tags
R2B51_RS14680R2B51_RS14685
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_009906147.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagR2B51_RS14685Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP137339.1Sequence record reported by the local genomic context database.
Genomic interval3 156 509-3 158 014 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 155 697-3 158 014 ntGCF_042449905::NZ_CP137339.1::G00044
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_042449905::NZ_CP137339.1::G00044Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP137339.1All displayed genes belong to this local TCS context.
Neighborhood span3 155 697-3 158 014 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 155 697 nt3 158 014 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
R2B51_RS14680GCF_042449905#R2B51_RS14680
RRunclassified
3 155 697-3 156 395 nt · Reverse (-)
R2B51_RS14685GCF_042449905#R2B51_RS14685
HKClassicCurrent focus
3 156 509-3 158 014 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0214035Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1468209
Simplified PFAM architecture for HKOC_1468209
PFAM domain coverage: 139 / 501 aa (27.7%)
1 aa501 aa
Cupin_2His_kinase
- Simplified architecture: Cupin_2 + His_kinase
- Raw architecture: Cupin_2[34-98] | His_kinase[303-376]
- Domain count: 2
- Matched identifier: HKOC_1468209
- Positioned domains: Cupin_2 34-98 ; His_kinase 303-376
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0214035
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_042449905
AssemblyASM4244990v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 52 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key