1 HAMP#1
166-239 aa · 74 aa · 15.6% of protein
Raw token
HAMP:166:0.00000000935:239:74:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
R2B51_RS02975
Histidine kinase, Classic
Clostridioides difficile · GCF_042449905
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042449905#R2B51_RS02975Stable P2CS identifier used across views.
GenomeGCF_042449905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 474 aa (52.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw token
HisKA:250:0.00000000435:315:66:643 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw token
HATPase_c:365:1.84e-25:471:107:109- Raw architecture: HAMP:166:0.00000000935:239:74:69#HisKA:250:0.00000000435:315:66:64#HATPase_c:365:1.84e-25:471:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_042449905::NZ_CP137339.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span558447-560582Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_042449905::NZ_CP137339.1::G00004Context members
R2B51_RS02970R2B51_RS02975
Partner locus tags
R2B51_RS02970R2B51_RS02975
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_077745009.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagR2B51_RS02975Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP137339.1Sequence record reported by the local genomic context database.
Genomic interval559 158-560 582 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span558 447-560 582 ntGCF_042449905::NZ_CP137339.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_042449905::NZ_CP137339.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP137339.1All displayed genes belong to this local TCS context.
Neighborhood span558 447-560 582 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
558 447 nt560 582 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
R2B51_RS02970GCF_042449905#R2B51_RS02970
RROmpR
558 447-559 139 nt · Forward (+)
R2B51_RS02975GCF_042449905#R2B51_RS02975
HKClassicCurrent focus
559 158-560 582 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002303425#BGU60_RS15325Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1676660
Simplified PFAM architecture for HKOC_1676660
PFAM domain coverage: 222 / 474 aa (46.8%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[189-238] | HisKA[251-315] | HATPase_c[365-471]
- Domain count: 3
- Matched identifier: HKOC_1676660
- Positioned domains: HAMP 189-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Representative gene: GCF_002303425#BGU60_RS15325
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_042449905
AssemblyASM4244990v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 52 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key