Gene detail

R2B51_RS02520

Histidine kinase, Classic

Clostridioides difficile · GCF_042449905

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_042449905#R2B51_RS02520Stable P2CS identifier used across views.
GenomeGCF_042449905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2828606Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_077744926.1 · MIST4 R2B51_RS02520RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 121-187 aa (67 aa)1HATPase_c: 239-338 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
121-187 aa · 67 aa · 19.5% of protein
Raw tokenHisKA:121:0.000000000143:187:67:64
2 HATPase_c#2
239-338 aa · 100 aa · 29.2% of protein
Raw tokenHATPase_c:239:2.58e-26:338:101:109
  • Raw architecture: HisKA:121:0.000000000143:187:67:64#HATPase_c:239:2.58e-26:338:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_042449905::NZ_CP137339.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span470083-471776Genomic interval covered by the local TCS group.
Context group IDGCF_042449905::NZ_CP137339.1::G00002
Context members
R2B51_RS02515R2B51_RS02520
Partner locus tags
R2B51_RS02515R2B51_RS02520
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_077744926.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagR2B51_RS02520Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP137339.1Sequence record reported by the local genomic context database.
Genomic interval470 745-471 776 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span470 083-471 776 ntGCF_042449905::NZ_CP137339.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_042449905::NZ_CP137339.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP137339.1All displayed genes belong to this local TCS context.
Neighborhood span470 083-471 776 nt1 694 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
470 083 nt471 776 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

R2B51_RS02515GCF_042449905#R2B51_RS02515
RROmpR

470 083-470 748 nt · Forward (+)

RefSeq WP_176074867.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2828606Run 6 · HK · 10 sequences
Representative sequenceGCF_002303425#BGU60_RS02100Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2828606

Simplified PFAM architecture for HKOC_2828606

PFAM domain coverage: 166 / 343 aa (48.4%)

1 aa343 aa
HisKA: 123-187 aaHisKAHATPase_c: 238-338 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[123-187] | HATPase_c[238-338]
  • Domain count: 2
  • Matched identifier: HKOC_2828606
  • Positioned domains: HisKA 123-187 ; HATPase_c 238-338
Cluster members and taxonomy
Visualization

Representative gene: GCF_002303425#BGU60_RS02100

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_042449905
AssemblyASM4244990v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 52 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key