Gene detail

ACD504_RS14455

Histidine kinase, Classic

Clostridioides difficile · GCF_041537845

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537845#ACD504_RS14455Stable P2CS identifier used across views.
GenomeGCF_041537845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1738097Run 6 · 48 sequences · id 100% · cov 80%
External referencesWP_021362275.1 · MIST4 ACD504_RS14455RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-466 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000243:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:1.03e-17:466:111:109
  • Raw architecture: HisKA:245:0.00000000000243:309:65:64#HATPase_c:357:1.03e-17:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_041537845::NZ_JBGOPI010000003.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span435991-438149Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD504_14455RefSeq proteinWP_021362275.1
Context group IDGCF_041537845::NZ_JBGOPI010000003.1::G00042
Context members
ACD504_RS14455ACD504_RS14460
Partner locus tags
ACD504_RS14455ACD504_RS14460
Partner old locus tags
ACD504_14455ACD504_14460
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021362275.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACD504_RS14455Primary locus identifier stored in the genes table.
Old locus tagACD504_14455Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPI010000003.1Sequence record reported by the local genomic context database.
Genomic interval435 991-437 397 nt1 407 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span435 991-438 149 ntGCF_041537845::NZ_JBGOPI010000003.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_041537845::NZ_JBGOPI010000003.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPI010000003.1All displayed genes belong to this local TCS context.
Neighborhood span435 991-438 149 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
435 991 nt438 149 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACD504_RS14455GCF_041537845#ACD504_RS14455
HKClassicCurrent focus

435 991-437 397 nt · Reverse (-)

Old locus ACD504_14455RefSeq WP_021362275.1
ACD504_RS14460GCF_041537845#ACD504_RS14460
RROmpR

437 442-438 149 nt · Reverse (-)

Old locus ACD504_14460RefSeq WP_009888460.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1738097Run 6 · HK · 48 sequences
Representative sequenceGCF_000448725#QAW_RS03270Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1738097

Simplified PFAM architecture for HKOC_1738097

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1738097
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS03270

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537845
AssemblyASM4153784v1 · Contighaploid
Genome composition4 172 076 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key