Gene detail

ACD504_RS08760

Histidine kinase, Classic

Clostridioides difficile · GCF_041537845

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537845#ACD504_RS08760Stable P2CS identifier used across views.
GenomeGCF_041537845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860210Run 6 · 351 sequences · id 100% · cov 80%
External referencesWP_011861320.1 · Q186U6 · MIST4 ACD504_RS08760RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-658 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:5.96e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000426:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:1.82e-23:658:103:109
  • Raw architecture: SBP_bac_3:58:5.96e-41:278:230:224#HisKA:446:0.0000000000000426:508:63:64#HATPase_c:557:1.82e-23:658:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_041537845::NZ_JBGOPI010000002.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span260899-263369Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD504_08760RefSeq proteinWP_011861320.1
Context group IDGCF_041537845::NZ_JBGOPI010000002.1::G00027
Context members
ACD504_RS08755ACD504_RS08760
Partner locus tags
ACD504_RS08755ACD504_RS08760
Partner old locus tags
ACD504_08755ACD504_08760
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861320.1Primary protein accession used for annex mappings.
UniProt accessionQ186U6Primary UniProt accession resolved in the annex database.
UniProt IDQ186U6_CLOD6Display identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACD504_RS08760Primary locus identifier stored in the genes table.
Old locus tagACD504_08760Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPI010000002.1Sequence record reported by the local genomic context database.
Genomic interval261 375-263 369 nt1 995 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span260 899-263 369 ntGCF_041537845::NZ_JBGOPI010000002.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_041537845::NZ_JBGOPI010000002.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPI010000002.1All displayed genes belong to this local TCS context.
Neighborhood span260 899-263 369 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
260 899 nt263 369 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACD504_RS08755GCF_041537845#ACD504_RS08755
RRCheY

260 899-261 375 nt · Reverse (-)

Old locus ACD504_08755RefSeq WP_372538186.1
ACD504_RS08760GCF_041537845#ACD504_RS08760
HKClassicCurrent focus

261 375-263 369 nt · Reverse (-)

Old locus ACD504_08760RefSeq WP_011861320.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860210Run 6 · HK · 351 sequences
Representative sequenceGCF_000009205#CD630_RS09465Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860210

Simplified PFAM architecture for HKOC_0860210

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860210
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS09465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537845
AssemblyASM4153784v1 · Contighaploid
Genome composition4 172 076 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key