Gene detail

ACD504_RS06690

Histidine kinase, Classic

Clostridioides difficile · GCF_041537845

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_041537845#ACD504_RS06690Stable P2CS identifier used across views.
GenomeGCF_041537845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842593Run 6 · 53 sequences · id 100% · cov 80%
External referencesWP_021363032.1 · MIST4 ACD504_RS06690RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000359:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:4.02e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000359:514:66:64#HATPase_c:565:4.02e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_041537845::NZ_JBGOPI010000001.1::G00017
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span1514609-1520334Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD504_06690RefSeq proteinWP_021363032.1
Context group IDGCF_041537845::NZ_JBGOPI010000001.1::G00017
Context members
ACD504_RS06675ACD504_RS06680ACD504_RS06685ACD504_RS06690ACD504_RS06695
Partner locus tags
ACD504_RS06675ACD504_RS06680ACD504_RS06685ACD504_RS06690ACD504_RS06695
Partner old locus tags
ACD504_06675ACD504_06680ACD504_06685ACD504_06690ACD504_06695

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021363032.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACD504_RS06690Primary locus identifier stored in the genes table.
Old locus tagACD504_06690Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPI010000001.1Sequence record reported by the local genomic context database.
Genomic interval1 517 570-1 519 585 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 514 609-1 520 334 ntGCF_041537845::NZ_JBGOPI010000001.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_041537845::NZ_JBGOPI010000001.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 514 609-1 520 334 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 514 609 nt1 520 334 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

ACD504_RS06675GCF_041537845#ACD504_RS06675
HKClassic

1 514 609-1 515 724 nt · Reverse (-)

Old locus ACD504_06675RefSeq WP_009891726.1
ACD504_RS06680GCF_041537845#ACD504_RS06680
RROmpR

1 515 760-1 516 458 nt · Reverse (-)

Old locus ACD504_06680RefSeq WP_021363030.1
ACD504_RS06685GCF_041537845#ACD504_RS06685
RROmpR

1 516 840-1 517 520 nt · Reverse (-)

Old locus ACD504_06685RefSeq WP_021363031.1
ACD504_RS06690GCF_041537845#ACD504_RS06690
HKClassicCurrent focus

1 517 570-1 519 585 nt · Reverse (-)

Old locus ACD504_06690RefSeq WP_021363032.1
ACD504_RS06695GCF_041537845#ACD504_RS06695
RROmpR

1 519 657-1 520 334 nt · Reverse (-)

Old locus ACD504_06695RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842593Run 6 · HK · 53 sequences
Representative sequenceGCF_000448725#QAW_RS17165Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842593

Simplified PFAM architecture for HKOC_0842593

PFAM domain coverage: 171 / 671 aa (25.5%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-668 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-668]
  • Domain count: 2
  • Matched identifier: HKOC_0842593
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-668
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS17165

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537845
AssemblyASM4153784v1 · Contighaploid
Genome composition4 172 076 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key