1 PAS_9#1
27-126 aa · 100 aa · 27.8% of protein
Raw token
PAS_9:27:0.0000012:126:103:102P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD557_RS00900
Histidine kinase, Classic
Clostridioides difficile · GCF_041537445
ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537445#ACD557_RS00900Stable P2CS identifier used across views.
GenomeGCF_041537445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_9HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 360 aa (75.3%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa360 aa
Domain-by-domain annotation3 items
2 HisKA#2
133-199 aa · 67 aa · 18.6% of protein
Raw token
HisKA:133:1.68e-18:199:67:643 HATPase_c#3
250-353 aa · 104 aa · 28.9% of protein
Raw token
HATPase_c:250:3.05e-30:353:104:109- Raw architecture: PAS_9:27:0.0000012:126:103:102#HisKA:133:1.68e-18:199:67:64#HATPase_c:250:3.05e-30:353:104:109
- Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041537445::NZ_JBGOPK010000001.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span206341-208350Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD557_00900RefSeq proteinWP_103887583.1
Context group ID
GCF_041537445::NZ_JBGOPK010000001.1::G00006Context members
ACD557_RS00900ACD557_RS00910
Partner locus tags
ACD557_RS00900ACD557_RS00910
Partner old locus tags
ACD557_00900ACD557_00910
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_103887583.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD557_RS00900Primary locus identifier stored in the genes table.
Old locus tagACD557_00900Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPK010000001.1Sequence record reported by the local genomic context database.
Genomic interval206 341-207 423 nt1 083 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span206 341-208 350 ntGCF_041537445::NZ_JBGOPK010000001.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537445::NZ_JBGOPK010000001.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPK010000001.1All displayed genes belong to this local TCS context.
Neighborhood span206 341-208 350 nt2 010 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
206 341 nt208 350 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACD557_RS00900GCF_041537445#ACD557_RS00900
HKClassicCurrent focus
206 341-207 423 nt · Reverse (-)
ACD557_RS00910GCF_041537445#ACD557_RS00910
RROmpR
207 658-208 350 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0213315Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2180212
Simplified PFAM architecture for HKOC_2180212
PFAM domain coverage: 324 / 429 aa (75.5%)
1 aa429 aa
HAMPPASHisKAHATPase_c
- Simplified architecture: HAMP + PAS + HisKA + HATPase_c
- Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
- Domain count: 4
- Matched identifier: HKOC_2180212
- Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0213315
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537445
AssemblyASM4153744v1 · Contighaploid
Genome composition4 213 622 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 43 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key