Gene detail

ACD557_RS00160

Histidine kinase, Classic

Clostridioides difficile · GCF_041537445

ClassHKTypeClassicLength911 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_041537445#ACD557_RS00160Stable P2CS identifier used across views.
GenomeGCF_041537445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0390792Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_372538317.1 · MIST4 ACD557_RS00160RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_c
Protein length911 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage284 / 911 aa (31.2%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa911 aa
PAS_9: 528-628 aa (101 aa)1HisKA: 654-725 aa (72 aa)2HATPase_c: 772-882 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_9#1
528-628 aa · 101 aa · 11.1% of protein
Raw tokenPAS_9:528:0.0000764:628:101:102
2 HisKA#2
654-725 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:654:0.00000000000000678:725:72:64
3 HATPase_c#3
772-882 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:772:3.38e-31:882:111:109
  • Raw architecture: PAS_9:528:0.0000764:628:101:102#HisKA:654:0.00000000000000678:725:72:64#HATPase_c:772:3.38e-31:882:111:109
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_041537445::NZ_JBGOPK010000001.1::G00001
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span31388-34123Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD557_00160RefSeq proteinWP_372538317.1
Context group IDGCF_041537445::NZ_JBGOPK010000001.1::G00001
Context members
ACD557_RS00160
Partner locus tags
ACD557_RS00160
Partner old locus tags
ACD557_00160
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_372538317.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACD557_RS00160Primary locus identifier stored in the genes table.
Old locus tagACD557_00160Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPK010000001.1Sequence record reported by the local genomic context database.
Genomic interval31 388-34 123 nt2 736 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span31 388-34 123 ntGCF_041537445::NZ_JBGOPK010000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_041537445::NZ_JBGOPK010000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPK010000001.1All displayed genes belong to this local TCS context.
Neighborhood span31 388-34 123 nt2 736 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
31 388 nt34 123 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

ACD557_RS00160GCF_041537445#ACD557_RS00160
HKClassicCurrent focus

31 388-34 123 nt · Reverse (-)

Old locus ACD557_00160RefSeq WP_372538317.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0390792Run 6 · HK · 1 sequences
Representative sequenceGCF_041537445#ACD557_RS00160The current gene is the representative for this cluster.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0390792

Simplified PFAM architecture for HKOC_0390792

PFAM domain coverage: 340 / 911 aa (37.3%)

1 aa911 aa
PAS_8: 302-354 aaPAS_8PAS_9: 528-631 aaPAS_9HisKA: 654-725 aaHisKAHATPase_c: 772-882 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[302-354] | PAS_9[528-631] | HisKA[654-725] | HATPase_c[772-882]
  • Domain count: 4
  • Matched identifier: HKOC_0390792
  • Positioned domains: PAS_8 302-354 ; PAS_9 528-631 ; HisKA 654-725 ; HATPase_c 772-882
Cluster members and taxonomy
Visualization

Representative gene: GCF_041537445#ACD557_RS00160

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537445
AssemblyASM4153744v1 · Contighaploid
Genome composition4 213 622 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 43 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key