1 HAMP#1
212-279 aa · 68 aa · 13.0% of protein
Raw token
HAMP:212:0.00000735:279:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD500_RS14465
Histidine kinase, Classic
Clostridioides difficile · GCF_041537425
ClassHKTypeClassicLength524 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537425#ACD500_RS14465Stable P2CS identifier used across views.
GenomeGCF_041537425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length524 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage215 / 524 aa (41.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa524 aa
Domain-by-domain annotation3 items
2 HisKA#2
289-347 aa · 59 aa · 11.3% of protein
Raw token
HisKA:289:5.55e-17:347:59:643 HATPase_c#3
395-482 aa · 88 aa · 16.8% of protein
Raw token
HATPase_c:395:1.08e-24:482:92:109- Raw architecture: HAMP:212:0.00000735:279:68:69#HisKA:289:5.55e-17:347:59:64#HATPase_c:395:1.08e-24:482:92:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041537425::NZ_JBGOPG010000001.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3143842-3146122Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD500_14465RefSeq proteinWP_372538596.1
Context group ID
GCF_041537425::NZ_JBGOPG010000001.1::G00043Context members
ACD500_RS14465ACD500_RS14470
Partner locus tags
ACD500_RS14465ACD500_RS14470
Partner old locus tags
ACD500_14465ACD500_14470
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_372538596.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD500_RS14465Primary locus identifier stored in the genes table.
Old locus tagACD500_14465Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPG010000001.1Sequence record reported by the local genomic context database.
Genomic interval3 143 842-3 145 416 nt1 575 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 143 842-3 146 122 ntGCF_041537425::NZ_JBGOPG010000001.1::G00043
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537425::NZ_JBGOPG010000001.1::G00043Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPG010000001.1All displayed genes belong to this local TCS context.
Neighborhood span3 143 842-3 146 122 nt2 281 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 143 842 nt3 146 122 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACD500_RS14465GCF_041537425#ACD500_RS14465
HKClassicCurrent focus
3 143 842-3 145 416 nt · Reverse (-)
ACD500_RS14470GCF_041537425#ACD500_RS14470
RROmpR
3 145 418-3 146 122 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_041537425#ACD500_RS14465The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1379340
Simplified PFAM architecture for HKOC_1379340
PFAM domain coverage: 150 / 524 aa (28.6%)
1 aa524 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-483]
- Domain count: 2
- Matched identifier: HKOC_1379340
- Positioned domains: HisKA 287-347 ; HATPase_c 395-483
Cluster members and taxonomy
Representative gene: GCF_041537425#ACD500_RS14465
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537425
AssemblyASM4153742v1 · Contighaploid
Genome composition4 154 450 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key