1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw token
HisKA:117:0.000000000161:177:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD500_RS00665
Histidine kinase, Classic
Clostridioides difficile · GCF_041537425
ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537425#ACD500_RS00665Stable P2CS identifier used across views.
GenomeGCF_041537425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw token
HATPase_c:222:6.69e-24:328:107:109- Raw architecture: HisKA:117:0.000000000161:177:61:64#HATPase_c:222:6.69e-24:328:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041537425::NZ_JBGOPG010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span135532-137194Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD500_00665RefSeq proteinWP_003434897.1
Context group ID
GCF_041537425::NZ_JBGOPG010000001.1::G00002Context members
ACD500_RS00660ACD500_RS00665
Partner locus tags
ACD500_RS00660ACD500_RS00665
Partner old locus tags
ACD500_00660ACD500_00665
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434897.1Primary protein accession used for annex mappings.
UniProt accessionQ181I8Primary UniProt accession resolved in the annex database.
UniProt IDQ181I8_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD500_RS00665Primary locus identifier stored in the genes table.
Old locus tagACD500_00665Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPG010000001.1Sequence record reported by the local genomic context database.
Genomic interval136 205-137 194 nt990 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span135 532-137 194 ntGCF_041537425::NZ_JBGOPG010000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537425::NZ_JBGOPG010000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPG010000001.1All displayed genes belong to this local TCS context.
Neighborhood span135 532-137 194 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
135 532 nt137 194 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACD500_RS00660GCF_041537425#ACD500_RS00660
RROmpR
135 532-136 218 nt · Forward (+)
ACD500_RS00665GCF_041537425#ACD500_RS00665
HKClassicCurrent focus
136 205-137 194 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS19070Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2857938
Simplified PFAM architecture for HKOC_2857938
PFAM domain coverage: 169 / 329 aa (51.4%)
1 aa329 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[116-177] | HATPase_c[222-328]
- Domain count: 2
- Matched identifier: HKOC_2857938
- Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS19070
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537425
AssemblyASM4153742v1 · Contighaploid
Genome composition4 154 450 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key