1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw token
HisKA:82:0.0000000761:144:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD536_RS00370
Histidine kinase, Classic
Clostridioides difficile · GCF_041537345
ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537345#ACD536_RS00370Stable P2CS identifier used across views.
GenomeGCF_041537345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw token
HATPase_c:196:2.39e-22:295:100:109- Raw architecture: HisKA:82:0.0000000761:144:63:64#HATPase_c:196:2.39e-22:295:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041537345::NZ_JBGOPJ010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span73905-75486Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD536_00370RefSeq proteinWP_003435311.1
Context group ID
GCF_041537345::NZ_JBGOPJ010000001.1::G00002Context members
ACD536_RS00365ACD536_RS00370
Partner locus tags
ACD536_RS00365ACD536_RS00370
Partner old locus tags
ACD536_00365ACD536_00370
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003435311.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RGV3Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RGV3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD536_RS00370Primary locus identifier stored in the genes table.
Old locus tagACD536_00370Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPJ010000001.1Sequence record reported by the local genomic context database.
Genomic interval74 578-75 486 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span73 905-75 486 ntGCF_041537345::NZ_JBGOPJ010000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537345::NZ_JBGOPJ010000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPJ010000001.1All displayed genes belong to this local TCS context.
Neighborhood span73 905-75 486 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
73 905 nt75 486 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACD536_RS00365GCF_041537345#ACD536_RS00365
RROmpR
73 905-74 576 nt · Forward (+)
ACD536_RS00370GCF_041537345#ACD536_RS00370
HKClassicCurrent focus
74 578-75 486 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_033840375#SIK50_RS12330Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2883601
Simplified PFAM architecture for HKOC_2883601
PFAM domain coverage: 165 / 304 aa (54.3%)
1 aa304 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[84-146] | HATPase_c[197-298]
- Domain count: 2
- Matched identifier: HKOC_2883601
- Positioned domains: HisKA 84-146 ; HATPase_c 197-298
Cluster members and taxonomy
Representative gene: GCF_033840375#SIK50_RS12330
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537345
AssemblyASM4153734v1 · Contighaploid
Genome composition4 141 476 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 44 · RR 48CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key