1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw token
HisKA:199:0.000000000961:258:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD265_RS05540
Histidine kinase, Classic
Clostridioides difficile · GCF_041537305
ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041537305#ACD265_RS05540Stable P2CS identifier used across views.
GenomeGCF_041537305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa417 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw token
HATPase_c:304:1.38e-21:410:107:109- Raw architecture: HisKA:199:0.000000000961:258:60:64#HATPase_c:304:1.38e-21:410:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041537305::NZ_JBGOPC010000001.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1183121-1185056Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD265_05540RefSeq proteinWP_074048246.1
Context group ID
GCF_041537305::NZ_JBGOPC010000001.1::G00018Context members
ACD265_RS05540ACD265_RS05545
Partner locus tags
ACD265_RS05540ACD265_RS05545
Partner old locus tags
ACD265_05540ACD265_05545
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_074048246.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD265_RS05540Primary locus identifier stored in the genes table.
Old locus tagACD265_05540Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPC010000001.1Sequence record reported by the local genomic context database.
Genomic interval1 183 121-1 184 374 nt1 254 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 183 121-1 185 056 ntGCF_041537305::NZ_JBGOPC010000001.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537305::NZ_JBGOPC010000001.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPC010000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 183 121-1 185 056 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 183 121 nt1 185 056 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACD265_RS05540GCF_041537305#ACD265_RS05540
HKClassicCurrent focus
1 183 121-1 184 374 nt · Reverse (-)
ACD265_RS05545GCF_041537305#ACD265_RS05545
RROmpR
1 184 352-1 185 056 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000531625#BN168_RS07520Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2293824
Simplified PFAM architecture for HKOC_2293824
PFAM domain coverage: 169 / 417 aa (40.5%)
1 aa417 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[196-258] | HATPase_c[305-410]
- Domain count: 2
- Matched identifier: HKOC_2293824
- Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Representative gene: GCF_000531625#BN168_RS07520
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537305
AssemblyASM4153730v1 · Contighaploid
Genome composition4 255 016 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key