Gene detail

ACD328_RS11355

Histidine kinase, Classic

Clostridioides difficile · GCF_041537245

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_041537245#ACD328_RS11355Stable P2CS identifier used across views.
GenomeGCF_041537245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842606Run 6 · 77 sequences · id 100% · cov 80%
External referencesWP_021395046.1 · MIST4 ACD328_RS11355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for ACD328_RS11355
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000367:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:3.87e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000367:514:66:64#HATPase_c:565:3.87e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_041537245::NZ_JBGOPB010000002.1::G00038
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span811201-814695Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD328_11355RefSeq proteinWP_021395046.1
Context group IDGCF_041537245::NZ_JBGOPB010000002.1::G00038
Context members
ACD328_RS11350ACD328_RS11355ACD328_RS11360
Partner locus tags
ACD328_RS11350ACD328_RS11355ACD328_RS11360
Partner old locus tags
ACD328_11350ACD328_11355ACD328_11360

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021395046.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACD328_RS11355Primary locus identifier stored in the genes table.
Old locus tagACD328_11355Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPB010000002.1Sequence record reported by the local genomic context database.
Genomic interval811 931-813 946 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span811 201-814 695 ntGCF_041537245::NZ_JBGOPB010000002.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_041537245::NZ_JBGOPB010000002.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPB010000002.1All displayed genes belong to this local TCS context.
Neighborhood span811 201-814 695 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
811 201 nt814 695 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

ACD328_RS11350GCF_041537245#ACD328_RS11350
RROmpR

811 201-811 881 nt · Reverse (-)

Old locus ACD328_11350RefSeq WP_021395045.1
ACD328_RS11355GCF_041537245#ACD328_RS11355
HKClassicCurrent focus

811 931-813 946 nt · Reverse (-)

Old locus ACD328_11355RefSeq WP_021395046.1
ACD328_RS11360GCF_041537245#ACD328_RS11360
RROmpR

814 018-814 695 nt · Reverse (-)

Old locus ACD328_11360RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842606Run 6 · HK · 77 sequences
Representative sequenceGCF_000451665#QS3_RS16235Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842606

Simplified PFAM architecture for HKOC_0842606

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842606
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451665#QS3_RS16235

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537245
AssemblyASM4153724v1 · Contighaploid
Genome composition4 359 791 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key