1 PAS_4#1
69-177 aa · 109 aa · 24.7% of protein
Raw token
PAS_4:69:0.000000000149:177:115:110P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD319_RS07580
Histidine kinase, Classic
Clostridioides difficile · GCF_041537165
ClassHKTypeClassicLength441 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_041537165#ACD319_RS07580Stable P2CS identifier used across views.
GenomeGCF_041537165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_4HisKAHATPase_c
Protein length441 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 441 aa (65.8%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa441 aa
Domain-by-domain annotation3 items
2 HisKA#2
186-255 aa · 70 aa · 15.9% of protein
Raw token
HisKA:186:0.00000000000000503:255:70:643 HATPase_c#3
302-412 aa · 111 aa · 25.2% of protein
Raw token
HATPase_c:302:1.01e-27:412:111:109- Raw architecture: PAS_4:69:0.000000000149:177:115:110#HisKA:186:0.00000000000000503:255:70:64#HATPase_c:302:1.01e-27:412:111:109
- Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_041537165::NZ_JBGOOZ010000001.1::G00027
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1702818-1704143Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD319_07580RefSeq proteinWP_372556338.1
Context group ID
GCF_041537165::NZ_JBGOOZ010000001.1::G00027Context members
ACD319_RS07580
Partner locus tags
ACD319_RS07580
Partner old locus tags
ACD319_07580
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_372556338.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD319_RS07580Primary locus identifier stored in the genes table.
Old locus tagACD319_07580Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOOZ010000001.1Sequence record reported by the local genomic context database.
Genomic interval1 702 818-1 704 143 nt1 326 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 702 818-1 704 143 ntGCF_041537165::NZ_JBGOOZ010000001.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537165::NZ_JBGOOZ010000001.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOOZ010000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 702 818-1 704 143 nt1 326 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 702 818 nt1 704 143 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ACD319_RS07580GCF_041537165#ACD319_RS07580
HKClassicCurrent focus
1 702 818-1 704 143 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_041537165#ACD319_RS07580The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2069475
Simplified PFAM architecture for HKOC_2069475
PFAM domain coverage: 290 / 441 aa (65.8%)
1 aa441 aa
PAS_4HisKAHATPase_c
- Simplified architecture: PAS_4 + HisKA + HATPase_c
- Raw architecture: PAS_4[69-177] | HisKA[186-255] | HATPase_c[302-412]
- Domain count: 3
- Matched identifier: HKOC_2069475
- Positioned domains: PAS_4 69-177 ; HisKA 186-255 ; HATPase_c 302-412
Cluster members and taxonomy
Representative gene: GCF_041537165#ACD319_RS07580
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537165
AssemblyASM4153716v1 · Contighaploid
Genome composition4 199 551 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key