Gene detail

ABCO99_RS02295

Histidine kinase, Classic

Clostridioides difficile · GCF_038754485

ClassHKTypeClassicLength335 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_038754485#ABCO99_RS02295Stable P2CS identifier used across views.
GenomeGCF_038754485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2848218Run 6 · 168 sequences · id 100% · cov 80%
External referencesWP_021367076.1 · A0A069AJD6 · MIST4 ABCO99_RS02295RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length335 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 335 aa (49.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa335 aa
HisKA: 122-175 aa (54 aa)1HATPase_c: 221-331 aa (111 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
122-175 aa · 54 aa · 16.1% of protein
Raw tokenHisKA:122:0.00000326:175:60:64
2 HATPase_c#2
221-331 aa · 111 aa · 33.1% of protein
Raw tokenHATPase_c:221:1.93e-20:331:111:109
  • Raw architecture: HisKA:122:0.00000326:175:60:64#HATPase_c:221:1.93e-20:331:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_038754485::NZ_JBBBLT010000001.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span543216-544891Genomic interval covered by the local TCS group.
Context group IDGCF_038754485::NZ_JBBBLT010000001.1::G00009
Context members
ABCO99_RS02290ABCO99_RS02295
Partner locus tags
ABCO99_RS02290ABCO99_RS02295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021367076.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AJD6Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AJD6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagABCO99_RS02295Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JBBBLT010000001.1Sequence record reported by the local genomic context database.
Genomic interval543 884-544 891 nt1 008 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span543 216-544 891 ntGCF_038754485::NZ_JBBBLT010000001.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_038754485::NZ_JBBBLT010000001.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBBBLT010000001.1All displayed genes belong to this local TCS context.
Neighborhood span543 216-544 891 nt1 676 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
543 216 nt544 891 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ABCO99_RS02290GCF_038754485#ABCO99_RS02290
RROmpR

543 216-543 887 nt · Forward (+)

RefSeq WP_021367068.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2848218Run 6 · HK · 168 sequences
Representative sequenceGCF_000448765#QC5_RS14880Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2848218

Simplified PFAM architecture for HKOC_2848218

PFAM domain coverage: 110 / 335 aa (32.8%)

1 aa335 aa
HATPase_c: 221-330 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[221-330]
  • Domain count: 1
  • Matched identifier: HKOC_2848218
  • Positioned domains: HATPase_c 221-330
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS14880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_038754485
AssemblyASM3875448v1 · Contighaploid
Genome composition4 221 801 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key