1 HisKA#1
88-154 aa · 67 aa · 21.4% of protein
Raw token
HisKA:88:0.000000000000215:154:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
WIS25_RS12520
Histidine kinase, Classic
Clostridioides difficile · GCF_037924525
ClassHKTypeClassicLength313 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_037924525#WIS25_RS12520Stable P2CS identifier used across views.
GenomeGCF_037924525Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length313 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 313 aa (56.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa313 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
200-308 aa · 109 aa · 34.8% of protein
Raw token
HATPase_c:200:8.75e-27:308:110:109- Raw architecture: HisKA:88:0.000000000000215:154:67:64#HATPase_c:200:8.75e-27:308:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_037924525::NZ_CP149715.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2820202-2822065Genomic interval covered by the local TCS group.
Identifiers
Old locus tagWIS25_12520RefSeq proteinWP_021362088.1
Context group ID
GCF_037924525::NZ_CP149715.1::G00040Context members
WIS25_RS12520WIS25_RS12525
Partner locus tags
WIS25_RS12520WIS25_RS12525
Partner old locus tags
WIS25_12520WIS25_12525
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021362088.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagWIS25_RS12520Primary locus identifier stored in the genes table.
Old locus tagWIS25_12520Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP149715.1Sequence record reported by the local genomic context database.
Genomic interval2 820 202-2 821 143 nt942 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 820 202-2 822 065 ntGCF_037924525::NZ_CP149715.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_037924525::NZ_CP149715.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP149715.1All displayed genes belong to this local TCS context.
Neighborhood span2 820 202-2 822 065 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 820 202 nt2 822 065 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
WIS25_RS12520GCF_037924525#WIS25_RS12520
HKClassicCurrent focus
2 820 202-2 821 143 nt · Reverse (-)
WIS25_RS12525GCF_037924525#WIS25_RS12525
RROmpR
2 821 373-2 822 065 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002302905#BGV10_RS07395Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2471040
Simplified PFAM architecture for HKOC_2471040
PFAM domain coverage: 175 / 397 aa (44.1%)
1 aa397 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[172-237] | HATPase_c[285-393]
- Domain count: 2
- Matched identifier: HKOC_2471040
- Positioned domains: HisKA 172-237 ; HATPase_c 285-393
Cluster members and taxonomy
Representative gene: GCF_002302905#BGV10_RS07395
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_037924525
AssemblyASM3792452v1 · Complete Genomehaploid
Genome composition3 951 046 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key