Gene detail

WIH66_RS00270

Histidine kinase, Classic

[Ruminococcus] torques · GCF_037247945

ClassHKTypeClassicLength618 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_037247945#WIH66_RS00270Stable P2CS identifier used across views.
GenomeGCF_037247945Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_0980067Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_055158908.1 · A0A414U1X1 · MIST4 WIH66_RS00270RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length618 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 618 aa (40.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa618 aa
HAMP: 326-394 aa (69 aa)1His_kinase: 409-489 aa (81 aa)2HATPase_c: 509-608 aa (100 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
326-394 aa · 69 aa · 11.2% of protein
Raw tokenHAMP:326:0.000000000928:394:69:69
2 His_kinase#2
409-489 aa · 81 aa · 13.1% of protein
Raw tokenHis_kinase:409:2.83e-28:489:81:80
3 HATPase_c#3
509-608 aa · 100 aa · 16.2% of protein
Raw tokenHATPase_c:509:0.0000000149:608:104:109
  • Raw architecture: HAMP:326:0.000000000928:394:69:69#His_kinase:409:2.83e-28:489:81:80#HATPase_c:509:0.0000000149:608:104:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_037247945::NZ_JAYCMQ010000023.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6174-9492Genomic interval covered by the local TCS group.
Context group IDGCF_037247945::NZ_JAYCMQ010000023.1::G00007
Context members
WIH66_RS00270WIH66_RS00275
Partner locus tags
WIH66_RS00270WIH66_RS00275
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055158908.1Primary protein accession used for annex mappings.
UniProt accessionA0A414U1X1Primary UniProt accession resolved in the annex database.
UniProt IDA0A414U1X1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagWIH66_RS00270Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAYCMQ010000023.1Sequence record reported by the local genomic context database.
Genomic interval6 174-8 030 nt1 857 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 174-9 492 ntGCF_037247945::NZ_JAYCMQ010000023.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_037247945::NZ_JAYCMQ010000023.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAYCMQ010000023.1All displayed genes belong to this local TCS context.
Neighborhood span6 174-9 492 nt3 319 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 174 nt9 492 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

WIH66_RS00275GCF_037247945#WIH66_RS00275
RRunclassified

8 023-9 492 nt · Forward (+)

RefSeq WP_238095069.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0980067Run 6 · HK · 33 sequences
Representative sequenceGCF_022132465#L0N16_RS12370Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0980067

Simplified PFAM architecture for HKOC_0980067

PFAM domain coverage: 227 / 618 aa (36.7%)

1 aa618 aa
HAMP: 351-394 aaHAMPHis_kinase: 409-489 aaHis_kinaseHATPase_c: 509-610 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[351-394] | His_kinase[409-489] | HATPase_c[509-610]
  • Domain count: 3
  • Matched identifier: HKOC_0980067
  • Positioned domains: HAMP 351-394 ; His_kinase 409-489 ; HATPase_c 509-610
Cluster members and taxonomy
Visualization

Representative gene: GCF_022132465#L0N16_RS12370

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 039 · GCF_037247945
AssemblyASM3724794v1 · Contighaploid
Genome composition2 404 359 bp · 42,0% GC[Ruminococcus] torques
Signal transduction countsGenes 46 · HK 21 · RR 23CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key