Gene detail

VH742_RS05705

Histidine kinase, Classic

Clostridioides difficile · GCF_036861275

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_036861275#VH742_RS05705Stable P2CS identifier used across views.
GenomeGCF_036861275Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504521Run 6 · 25 sequences · id 100% · cov 80%
External referencesWP_050573509.1 · MIST4 VH742_RS05705RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000618:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:3.67e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:1.24e-25:495:106:109
  • Raw architecture: HAMP:212:0.00000618:279:68:69#HisKA:289:3.67e-17:347:59:64#HATPase_c:395:1.24e-25:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_036861275::NZ_JAYJMP010000003.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2450-4643Genomic interval covered by the local TCS group.
Context group IDGCF_036861275::NZ_JAYJMP010000003.1::G00025
Context members
VH742_RS05705VH742_RS05710
Partner locus tags
VH742_RS05705VH742_RS05710
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_050573509.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagVH742_RS05705Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAYJMP010000003.1Sequence record reported by the local genomic context database.
Genomic interval2 450-3 937 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 450-4 643 ntGCF_036861275::NZ_JAYJMP010000003.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_036861275::NZ_JAYJMP010000003.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAYJMP010000003.1All displayed genes belong to this local TCS context.
Neighborhood span2 450-4 643 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 450 nt4 643 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504521Run 6 · HK · 25 sequences
Representative sequenceGCF_000449185#QCW_RS04900Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504521

Simplified PFAM architecture for HKOC_1504521

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504521
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS04900

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 25 over 25 total members. Page 1 / 1.

GCF_000449185#QCW_RS04900 (representative)
QCW_RS04900 · HK · Classic
RefSeq: WP_050573509.1
GCF_001704755#DCQ03_RS02380
DCQ03_RS02380 · HK · Classic
RefSeq: WP_050573509.1
GCF_001704795#DCQ01_RS08975
DCQ01_RS08975 · HK · Classic
RefSeq: WP_050573509.1
GCF_001704805#DCP99_RS14580
DCP99_RS14580 · HK · Classic
RefSeq: WP_050573509.1
GCF_003456975#CDIF102859_RS05570
CDIF102859_RS05570 · HK · Classic
RefSeq: WP_050573509.1
GCF_003457015#CDIF102860_RS06020
CDIF102860_RS06020 · HK · Classic
RefSeq: WP_050573509.1
GCF_003457035#CDIF102978_RS06020
CDIF102978_RS06020 · HK · Classic
RefSeq: WP_050573509.1
GCF_004314505#E0O34_RS16110
E0O34_RS16110 · HK · Classic
RefSeq: WP_050573509.1
GCF_004314745#E0O51_RS12890
E0O51_RS12890 · HK · Classic
RefSeq: WP_050573509.1
GCF_004315765#E0P52_RS08195
E0P52_RS08195 · HK · Classic
RefSeq: WP_050573509.1
GCF_012030175#GSQ43_RS06340
GSQ43_RS06340 · HK · Classic
RefSeq: WP_050573509.1
GCF_019426665#K1N14_RS06910
K1N14_RS06910 · HK · Classic
RefSeq: WP_050573509.1
GCF_024260215#NMF84_RS15410
NMF84_RS15410 · HK · Classic
RefSeq: WP_050573509.1
GCF_028597315#PSM44_RS07545
PSM44_RS07545 · HK · Classic
RefSeq: WP_050573509.1
GCF_033840445#SIK48_RS07770
SIK48_RS07770 · HK · Classic
RefSeq: WP_050573509.1
GCF_036017135#VXE66_RS14370
VXE66_RS14370 · HK · Classic
RefSeq: WP_050573509.1
GCF_036861275#VH742_RS05705
VH742_RS05705 · HK · Classic
RefSeq: WP_050573509.1
GCF_038754145#ABCP49_RS15440
ABCP49_RS15440 · HK · Classic
RefSeq: WP_050573509.1
GCF_038755145#ABCR36_RS09605
ABCR36_RS09605 · HK · Classic
RefSeq: WP_050573509.1
GCF_900096045#DK464_RS10285
DK464_RS10285 · HK · Classic
RefSeq: WP_050573509.1
GCF_900165935#B2B89_RS15495
B2B89_RS15495 · HK · Classic
RefSeq: WP_050573509.1
GCF_900165975#B2A22_RS15830
B2A22_RS15830 · HK · Classic
RefSeq: WP_050573509.1
GCF_900166005#B2A70_RS15775
B2A70_RS15775 · HK · Classic
RefSeq: WP_050573509.1
GCF_900166015#B2C46_RS15290
B2C46_RS15290 · HK · Classic
RefSeq: WP_050573509.1
GCF_901004505#FJF26_RS14680
FJF26_RS14680 · HK · Classic
RefSeq: WP_050573509.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_036861275
AssemblyASM3686127v1 · Contighaploid
Genome composition4 012 729 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 42 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key