1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000574:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LFA86_RS08345
Histidine kinase, Classic
Clostridioides difficile · GCF_036698175
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_036698175#LFA86_RS08345Stable P2CS identifier used across views.
GenomeGCF_036698175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:3.29e-30:668:104:109- Raw architecture: HisKA:449:0.00000000574:514:66:64#HATPase_c:565:3.29e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_036698175::NZ_JAJBXB010000008.1::G00052
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span66450-72174Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_036698175::NZ_JAJBXB010000008.1::G00052Context members
LFA86_RS08340LFA86_RS08345LFA86_RS08350LFA86_RS08355LFA86_RS08360
Partner locus tags
LFA86_RS08340LFA86_RS08345LFA86_RS08350LFA86_RS08355LFA86_RS08360
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_332974088.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLFA86_RS08345Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAJBXB010000008.1Sequence record reported by the local genomic context database.
Genomic interval67 199-69 214 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span66 450-72 174 ntGCF_036698175::NZ_JAJBXB010000008.1::G00052
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_036698175::NZ_JAJBXB010000008.1::G00052Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJBXB010000008.1All displayed genes belong to this local TCS context.
Neighborhood span66 450-72 174 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
66 450 nt72 174 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
LFA86_RS08340GCF_036698175#LFA86_RS08340
RROmpR
66 450-67 127 nt · Forward (+)
LFA86_RS08345GCF_036698175#LFA86_RS08345
HKClassicCurrent focus
67 199-69 214 nt · Forward (+)
LFA86_RS08350GCF_036698175#LFA86_RS08350
RROmpR
69 264-69 944 nt · Forward (+)
LFA86_RS08355GCF_036698175#LFA86_RS08355
RROmpR
70 325-71 023 nt · Forward (+)
LFA86_RS08360GCF_036698175#LFA86_RS08360
HKClassic
71 059-72 174 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_036698175#LFA86_RS08345The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0844504
Simplified PFAM architecture for HKOC_0844504
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0844504
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_036698175#LFA86_RS08345
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_036698175
AssemblyASM3669817v1 · Contighaploid
Genome composition4 198 386 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 50 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key