Gene detail

V3Q53_RS17370

Histidine kinase, Classic

Clostridioides difficile · GCF_036443075

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_036443075#V3Q53_RS17370Stable P2CS identifier used across views.
GenomeGCF_036443075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783624Run 6 · 384 sequences · id 100% · cov 80%
External referencesWP_009888322.1 · A0A0H3MZ97 · MIST4 V3Q53_RS17370RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
HAMP: 170-237 aa (68 aa)1HisKA: 249-308 aa (60 aa)2HATPase_c: 355-439 aa (85 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000177:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000472:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.00000000000000871:439:88:109
  • Raw architecture: HAMP:170:0.00000000000177:237:68:69#HisKA:249:0.000000000472:308:61:64#HATPase_c:355:0.00000000000000871:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_036443075::NZ_JAZGZO010000027.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2509-4543Genomic interval covered by the local TCS group.
Identifiers
Old locus tagV3Q53_17370RefSeq proteinWP_009888322.1
Context group IDGCF_036443075::NZ_JAZGZO010000027.1::G00038
Context members
V3Q53_RS17370V3Q53_RS17375
Partner locus tags
V3Q53_RS17370V3Q53_RS17375
Partner old locus tags
V3Q53_17370V3Q53_17375
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888322.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ97Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ97_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagV3Q53_RS17370Primary locus identifier stored in the genes table.
Old locus tagV3Q53_17370Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAZGZO010000027.1Sequence record reported by the local genomic context database.
Genomic interval2 509-3 903 nt1 395 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 509-4 543 ntGCF_036443075::NZ_JAZGZO010000027.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_036443075::NZ_JAZGZO010000027.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAZGZO010000027.1All displayed genes belong to this local TCS context.
Neighborhood span2 509-4 543 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 509 nt4 543 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

V3Q53_RS17370GCF_036443075#V3Q53_RS17370
HKClassicCurrent focus

2 509-3 903 nt · Reverse (-)

Old locus V3Q53_17370RefSeq WP_009888322.1
V3Q53_RS17375GCF_036443075#V3Q53_RS17375
RROmpR

3 896-4 543 nt · Reverse (-)

Old locus V3Q53_17375RefSeq WP_009888321.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783624Run 6 · HK · 384 sequences
Representative sequenceGCF_000003215#QAC_RS0202630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783624

Simplified PFAM architecture for HKOC_1783624

PFAM domain coverage: 145 / 464 aa (31.3%)

1 aa464 aa
HisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 2
  • Matched identifier: HKOC_1783624
  • Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_036443075
AssemblyASM3644307v1 · Contighaploid
Genome composition4 071 012 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key