Gene detail

P4U35_RS25220

Histidine kinase, Classic

Bacillus mycoides · GCF_036211545

ClassHKTypeClassicLength352 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_036211545#P4U35_RS25220Stable P2CS identifier used across views.
GenomeGCF_036211545Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_2788665Run 6 · 86 sequences · id 100% · cov 80%
External referencesWP_002128066.1 · J8I5Q2 · MIST4 P4U35_RS25220RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length352 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 352 aa (70.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa352 aa
HAMP: 39-109 aa (71 aa)1HisKA: 120-185 aa (66 aa)2HATPase_c: 238-348 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
39-109 aa · 71 aa · 20.2% of protein
Raw tokenHAMP:39:0.000000001:109:71:69
2 HisKA#2
120-185 aa · 66 aa · 18.8% of protein
Raw tokenHisKA:120:9.8e-18:185:66:64
3 HATPase_c#3
238-348 aa · 111 aa · 31.5% of protein
Raw tokenHATPase_c:238:1.62e-25:348:111:109
  • Raw architecture: HAMP:39:0.000000001:109:71:69#HisKA:120:9.8e-18:185:66:64#HATPase_c:238:1.62e-25:348:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_036211545::NZ_JARMBU010000030.1::G00070
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1000-2768Genomic interval covered by the local TCS group.
Identifiers
Old locus tagP4U35_25160RefSeq proteinWP_002128066.1
Context group IDGCF_036211545::NZ_JARMBU010000030.1::G00070
Context members
P4U35_RS25220P4U35_RS25225
Partner locus tags
P4U35_RS25220P4U35_RS25225
Partner old locus tags
P4U35_25160P4U35_25165
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002128066.1Primary protein accession used for annex mappings.
UniProt accessionJ8I5Q2Primary UniProt accession resolved in the annex database.
UniProt IDJ8I5Q2_BACCEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagP4U35_RS25220Primary locus identifier stored in the genes table.
Old locus tagP4U35_25160Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JARMBU010000030.1Sequence record reported by the local genomic context database.
Genomic interval1 000-2 058 nt1 059 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 000-2 768 ntGCF_036211545::NZ_JARMBU010000030.1::G00070

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_036211545::NZ_JARMBU010000030.1::G00070

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JARMBU010000030.1All displayed genes belong to this local TCS context.
Neighborhood span1 000-2 768 nt1 769 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 000 nt2 768 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

P4U35_RS25220GCF_036211545#P4U35_RS25220
HKClassicCurrent focus

1 000-2 058 nt · Reverse (-)

Old locus P4U35_25160RefSeq WP_002128066.1
P4U35_RS25225GCF_036211545#P4U35_RS25225
RROmpR

2 055-2 768 nt · Reverse (-)

Old locus P4U35_25165RefSeq WP_002017159.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2788665Run 6 · HK · 86 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS14455Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2788665

Simplified PFAM architecture for HKOC_2788665

PFAM domain coverage: 230 / 352 aa (65.3%)

1 aa352 aa
HAMP: 56-109 aaHAMPHisKA: 121-185 aaHisKAHATPase_c: 238-348 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[56-109] | HisKA[121-185] | HATPase_c[238-348]
  • Domain count: 3
  • Matched identifier: HKOC_2788665
  • Positioned domains: HAMP 56-109 ; HisKA 121-185 ; HATPase_c 238-348
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS14455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_036211545
AssemblyASM3621154v1 · Scaffoldhaploid
Genome composition5 565 022 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 133 · HK 70 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key